Organization and Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($)					1 Months Ended			3 Months Ended		9 Months Ended
	Nov. 01, 2024	May 28, 2024	Mar. 04, 2024	Feb. 12, 2024	Mar. 31, 2024	Jun. 30, 2023	Apr. 30, 2022	Sep. 30, 2024	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023	Dec. 31, 2023
Organization And Summary Of Significant Accounting Policies [Line Items]
Cash and investments in marketable securities								$ 249,032,000		$ 249,032,000		$ 329,441,000
Proceeds from issuance of pre-funded warrant										30,000,000	$ 0
Accounts receivable, credit loss expense (reversal)								$ 0	$ 0	$ 0	$ 0
Bristol Myers Squibb Company
Organization And Summary Of Significant Accounting Policies [Line Items]
Sale of stock repurchased cash consideration				$ 3,000,000
Sale of stock shares repurchased				8,300,000
Securities Purchase Agreement | TCG Crossover Fund II, L.P.
Organization And Summary Of Significant Accounting Policies [Line Items]
Proceeds from issuance of pre-funded warrant			$ 30,000,000		$ 30,000,000
Effective date of warrant		Jun. 05, 2024
2020 Purchase and Sale Agreement
Organization And Summary Of Significant Accounting Policies [Line Items]
Amount exchanged to remove cap on royalties			$ 15,000,000
Asset Purchase Agreement | Asset Acquisition By Ampersand Capital Partners | Subsequent event
Organization And Summary Of Significant Accounting Policies [Line Items]
Proceeds from sale of assets	$ 70,000,000
Ownership interest received	20.00%
Pre-Funded Warrant | Securities Purchase Agreement | TCG Crossover Fund II, L.P.
Organization And Summary Of Significant Accounting Policies [Line Items]
Number of warrants issued to be purchase common shares			25,000,000		25,000,000
Shares issued, price per share			$ 1.2		$ 1.2
Pre-Funded Warrant | Securities Purchase Agreement | TCG Crossover Fund II, L.P. | Maximum
Organization And Summary Of Significant Accounting Policies [Line Items]
Resale of common stock issuable upon exercise of warrant		25,000,000
Employee Severance | 2022 Restructuring Plan
Organization And Summary Of Significant Accounting Policies [Line Items]
Workforce termination, percentage							70.00%
Employee Severance | 2023 Restructuring Plan
Organization And Summary Of Significant Accounting Policies [Line Items]
Workforce termination, percentage						60.00%