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Organization and Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
May 28, 2024
Mar. 04, 2024
Feb. 12, 2024
Mar. 31, 2024
Jun. 30, 2023
Apr. 30, 2022
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Dec. 31, 2023
Organization And Summary Of Significant Accounting Policies [Line Items]                      
Cash and investments in marketable securities             $ 290,640,000   $ 290,640,000   $ 329,441,000
Proceeds from issuance of pre-funded warrant                 30,000,000 $ 0  
Accounts receivable, credit loss expense (reversal)             $ 0 $ 0 $ 0 $ 0  
Bristol Myers Squibb Company                      
Organization And Summary Of Significant Accounting Policies [Line Items]                      
Sale of stock repurchased cash consideration     $ 3,000,000                
Sale of stock shares repurchased     8,300,000                
Securities Purchase Agreement | TCG Crossover Fund II, L.P.                      
Organization And Summary Of Significant Accounting Policies [Line Items]                      
Proceeds from issuance of pre-funded warrant   $ 30,000,000   $ 30,000,000              
Effective date of warrant Jun. 05, 2024                    
2020 Purchase and Sale Agreement                      
Organization And Summary Of Significant Accounting Policies [Line Items]                      
Amount exchanged to remove cap on royalties   $ 15,000,000                  
Pre-Funded Warrant | Securities Purchase Agreement | TCG Crossover Fund II, L.P.                      
Organization And Summary Of Significant Accounting Policies [Line Items]                      
Number of warrants issued to be purchase common shares   25,000,000   25,000,000              
Shares issued, price per share   $ 1.2   $ 1.2              
Pre-Funded Warrant | Securities Purchase Agreement | TCG Crossover Fund II, L.P. | Maximum                      
Organization And Summary Of Significant Accounting Policies [Line Items]                      
Resale of common stock issuable upon exercise of warrant 25,000,000                    
Employee Severance | 2022 Restructuring Plan                      
Organization And Summary Of Significant Accounting Policies [Line Items]                      
Workforce termination, percentage           70.00%          
Employee Severance | 2023 Restructuring Plan                      
Organization And Summary Of Significant Accounting Policies [Line Items]                      
Workforce termination, percentage         60.00%