Liabilities Related to the Sales of Future Royalties - Additional Information (Details) $ in Thousands				3 Months Ended	12 Months Ended
	Mar. 01, 2024 USD ($)	Dec. 16, 2020 USD ($)	Feb. 24, 2012 USD ($)	Dec. 31, 2021 USD ($)	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)
Liability Related to the Sale of Future Royalties [Line Items]
Non-cash loss on revaluation of liability related to the sale of future royalties					$ 0	$ 0	$ 24,410
2012 Purchase and Sale Agreement
Liability Related to the Sale of Future Royalties [Line Items]
Proceeds from sale of royalty rights			$ 124,000
2012 Purchase and Sale Agreement | Future Royalties
Liability Related to the Sale of Future Royalties [Line Items]
Fair value of liabilities					$ 84,700
Non-cash loss on revaluation of liability related to the sale of future royalties				$ 23,500
Transaction costs related to revised royalty payments				$ 900
2020 Purchase and Sale Agreement
Liability Related to the Sale of Future Royalties [Line Items]
Proceeds from sale of royalty rights		$ 150,000
Payment of transaction related to purchase and sale agreement		210,000
Payment of transaction related to purchase and sale agreement if threshold is not achieved		$ 240,000
2020 Purchase and Sale Agreement | Subsequent Event
Liability Related to the Sale of Future Royalties [Line Items]
Amount exchanged to remove cap on royalties	$ 15,000
2020 Purchase and Sale Agreement | Measurement Input, Discount Rate
Liability Related to the Sale of Future Royalties [Line Items]
Royalties liability, measurement input					0.17
2020 Purchase and Sale Agreement | Measurement Input, Interest Rate
Liability Related to the Sale of Future Royalties [Line Items]
Royalties liability, measurement input					0.30
Pursuant to the 2012 Purchase and Sale Agreement
Liability Related to the Sale of Future Royalties [Line Items]
Payment made for milestone not achieved year one						$ 10,000
Payment made for milestone not achieved year two					$ 10,000