Organization and Summary of Significant Accounting Policies (Details) - USD ($) shares in Millions	1 Months Ended		12 Months Ended
	Jun. 30, 2023	Apr. 30, 2022	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Organization And Summary Of Significant Accounting Policies [Line Items]
Cash and investments in marketable securities			$ 329,441,000	$ 504,977,000
Total revenue			90,122,000	$ 92,055,000	$ 101,907,000
Accounts receivable, credit loss expense (reversal)			$ 0
Employee Severance | 2022 Restructuring Plan
Organization And Summary Of Significant Accounting Policies [Line Items]
Workforce termination, percentage		70.00%
Employee Severance | 2023 Restructuring Plan
Organization And Summary Of Significant Accounting Policies [Line Items]
Workforce termination, percentage	60.00%
Stock Options, RSUs and PSUs
Organization And Summary Of Significant Accounting Policies [Line Items]
Weighted average antidilutive securities excluded from computation of earnings per share (in shares)			20.4	21.2	18.4
Cash And NonCash Royalties
Organization And Summary Of Significant Accounting Policies [Line Items]
Total revenue			$ 68,900,000	$ 69,800,000	$ 77,700,000
Buildings
Organization And Summary Of Significant Accounting Policies [Line Items]
Property and equipment estimated useful lives			20 years
Minimum | Manufacturing equipment
Organization And Summary Of Significant Accounting Policies [Line Items]
Property and equipment estimated useful lives			3 years
Maximum | Manufacturing equipment
Organization And Summary Of Significant Accounting Policies [Line Items]
Property and equipment estimated useful lives			10 years