Stock-Based Compensation (Details) (USD $) In Thousands	3 Months Ended	6 Months Ended
Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
Total stock-based compensation expense
Total stock-based compensation	$ 4,880	$ 4,361	$ 9,682	$ 8,105
Cost of goods sold [Member]
Total stock-based compensation expense
Total stock-based compensation	330	229	662	435
Research and development expense [Member]
Total stock-based compensation expense
Total stock-based compensation	2,120	1,734	4,089	3,301
General and administrative expense [Member]
Total stock-based compensation expense
Total stock-based compensation	$ 2,430	$ 2,398	$ 4,931	$ 4,369

Represents the expense recognized during the period arising from share-based compensation arrangements (for example, shares of stock, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Statement of Financial Accounting Standard (FAS)
-Number 123R
-Paragraph 64
-Subparagraph b

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Statement of Financial Accounting Standard (FAS)
-Number 123R
-Paragraph A240
-Subparagraph g(1)

Reference 3: http://www.xbrl.org/2003/role/presentationRef
-Publisher SEC
-Name Staff Accounting Bulletin (SAB)
-Number Topic 14
-Section F

Name:	us-gaap_AllocatedShareBasedCompensationExpense
Namespace Prefix:	us-gaap
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration