Restructuring, Impairment and Other Costs of Terminated Program - Summary of Restructuring Costs (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Restructuring and Related Activities [Abstract]
Clinical trial expense, other third-party and employee costs for the wind down of the bempegaldesleukin program	$ 31,693
Severance and benefit expense	30,904
Impairment of right-of-use assets and property, plant and equipment	65,761	$ 0	$ 0
(Gain) loss on sale or disposal of property, plant and equipment, net	(3,326)	$ 0	$ 0
Contract termination and other restructuring costs	10,898
Restructuring, impairment and other costs of terminated program	$ 135,930