Operating Leases - Additional Information (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2022 USD ($) ft²	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)
Leases [Line Items]
Impairment of right-of-use assets and property, plant and equipment	$ 65,761	$ 0	$ 0
Operating lease, payments	$ 20,100	$ 16,800	$ 16,200
Weighted average remaining lease term	7 years 1 month 6 days
Weighted average discount rate, percent	5.80%
Subleases aggregate lease payments	$ 10,500
Sublease Property, Plant And Equipment
Leases [Line Items]
Impairment of right-of-use assets and property, plant and equipment	$ 54,590
Mission Bay Facility
Leases [Line Items]
Lease space (in sq ft) | ft²	155,215
Third Street Facility
Leases [Line Items]
Lease space (in sq ft) | ft²	135,936