Restructuring, Impairment and Other Costs of Terminated Program (Tables)

12 Months Ended

Dec. 31, 2022

Restructuring and Related Activities [Abstract]

Schedule of Restructuring, Impairment and Other Costs of Terminated Program

Restructuring, impairment and other costs of terminated program includes the following (in thousands):

	Year Ended December 31, 2022
Clinical trial expense, other third-party and employee costs for the wind down of the bempegaldesleukin program	$	31,693
Severance and benefit expense	30,904
Impairment of right-of-use assets and property, plant and equipment	65,761
(Gain) loss on sale or disposal of property, plant and equipment, net	(3,326)
Contract termination and other restructuring costs	10,898
Restructuring, impairment and other costs of terminated program	$	135,930

The following table provides details regarding the severance and other termination benefit expense. We present the liability, which we paid in January 2023, in accrued compensation on our Consolidated Balance Sheet (in thousands):

	Year Ended December 31, 2022
	No service period		Service period required		Total
Liability balance as of March 31, 2022	$	—	$	—	$	—
Expense recognized during the period	22,993		7,911		30,904
Payments during the period	(22,993)		(4,612)		(27,605)
Liability balance as of December 31, 2022	$	—	$	3,299	$	3,299

We recorded impairment charges as follows (in thousands):

	Year Ended December 31, 2022
	Operating Lease Right-of-Use Assets		Property, Plant and Equipment		Total
Net book value of impaired sublease assets as of May 31, 2022	$	72,481	$	16,348	$	88,829
Less: Fair value of impaired sublease assets — Level 3 of Fair Value Hierarchy	(16,174)		(4,780)		(20,954)
Book value in excess of fair value	56,307		11,568		67,875
Less: Amounts recorded as amortization between May 31 and December 31, 2022 for Third St. facility	(1,717)		(397)		(2,114)
Total impairment of sublease assets	$	54,590	$	11,171	$	65,761

Schedule of Property, Plant and Equipment

Property, plant and equipment consists of the following (in thousands):

	December 31,
	2022		2021
Building and leasehold improvements	$	74,889	$	97,385
Laboratory equipment	24,243		42,704
Computer equipment and software	26,205		28,829
Manufacturing equipment	25,052		22,374
Furniture, fixtures, and other	4,263		10,094
Depreciable property, plant and equipment at cost	154,652		201,386
Less: accumulated depreciation	(124,731)		(148,039)
Depreciable property, plant and equipment, net	29,921		53,347
Construction-in-progress	2,530		7,163
Property, plant and equipment, net	$	32,451	$	60,510

We recorded the gains and losses as follows (in thousands):

	Year Ended December 31, 2022
Proceeds from sales		$	13,196
Net book value of assets		9,870
Total (gain) loss on sale or disposal of property, plan and equipment, net		(3,326)