Liabilities Related to the Sales of Future Royalties (Tables)

12 Months Ended

Dec. 31, 2022

Liability Related To Sale Of Potential Future Royalties [Abstract]

Schedule of Liability Related to Potential Future Royalties

The following table shows the activity within the liability account of each arrangement (in thousands):

	Year-Ended December 31, 2022						Period from inception to December 31, 2022
	2012 Purchase and Sale Agreement		2020 Purchase and Sale Agreement		Total		2012 Purchase and Sale Agreement		2020 Purchase and Sale Agreement		Total
Liabilities related to the sales of future royalties—beginning balance	$	78,282	$	120,062	$	198,344	$	—	$	—	$	—
Royalty monetization proceeds	—		—		—		124,000		150,000		274,000
Non-cash royalty revenue	(33,865)		(35,929)		(69,794)		(316,523)		(86,722)		(403,245)
Non-cash interest expense	10,750		18,161		28,911		234,168		39,016		273,184
Payments to RPI	—		—		—		(10,000)		—		(10,000)
Loss on revaluation of liability related to the sale of future royalties	—				—		23,522		—		23,522
Liabilities related to the sales of future royalties – ending balance	55,167		102,294		157,461		55,167		102,294		157,461
Less: unamortized transaction costs	—		(2,083)		(2,083)		—		(2,083)		(2,083)
Liabilities related to the sales of future royalties, net	$	55,167	$	100,211	$	155,378	$	55,167	$	100,211	$	155,378