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Restructuring, Impairment and Other Costs of Terminated Program - Sublease Information (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2022
Sep. 30, 2021
Restructuring Cost and Reserve [Line Items]      
Impairment expense for facilities   $ 53,401  
Impairment of other property, plant and equipment   5,120  
Total impairment of right-of-use assets and property, plant and equipment $ 1,200 58,521 $ 0
Reported Value Measurement      
Restructuring Cost and Reserve [Line Items]      
Property, plant and equipment and Operating lease right-of-use assets 90,539 90,539  
Property, Plant and Equipment      
Restructuring Cost and Reserve [Line Items]      
Impairment expense for facilities   9,372  
Impairment of other property, plant and equipment   5,120  
Total impairment of right-of-use assets and property, plant and equipment   14,492  
Property, Plant and Equipment | Reported Value Measurement      
Restructuring Cost and Reserve [Line Items]      
Property, plant and equipment and Operating lease right-of-use assets 16,348 16,348  
Operating Lease Right-of-Use Assets      
Restructuring Cost and Reserve [Line Items]      
Impairment expense for facilities   44,029  
Total impairment of right-of-use assets and property, plant and equipment   44,029  
Operating Lease Right-of-Use Assets | Reported Value Measurement      
Restructuring Cost and Reserve [Line Items]      
Property, plant and equipment and Operating lease right-of-use assets 74,191 74,191  
Fair Value, Level 3 | Estimate of Fair Value Measurement      
Restructuring Cost and Reserve [Line Items]      
Property, plant and equipment and Operating lease right-of-use assets 37,138 37,138  
Fair Value, Level 3 | Property, Plant and Equipment | Estimate of Fair Value Measurement      
Restructuring Cost and Reserve [Line Items]      
Property, plant and equipment and Operating lease right-of-use assets 6,976 6,976  
Fair Value, Level 3 | Operating Lease Right-of-Use Assets | Estimate of Fair Value Measurement      
Restructuring Cost and Reserve [Line Items]      
Property, plant and equipment and Operating lease right-of-use assets $ 30,162 $ 30,162