Stock-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2022

Share-Based Payment Arrangement [Abstract]

Schedule of Stock-Based Compensation Expense

We recognized total stock-based compensation expense in our Condensed Consolidated Statements of Operations as follows (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2022		2021		2022		2021
Cost of goods sold	$	720	$	688	$	2,037	$	2,131
Research and development	5,422		14,138		22,215		41,779
General and administrative	5,369		9,831		18,401		28,359
Restructuring, impairment and other costs of terminated program	1,007		—		1,929		—
Total stock-based compensation	$	12,518	$	24,657	$	44,582	$	72,269

Schedule of Share-based Compensation, Activity

We issued stock-based awards of our common stock as follows (shares in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2022		2021		2022		2021
Options granted	5,890		397		6,019		674
Weighted-average grant-date fair value of options granted	$	3.23	$	9.36	$	3.24	$	9.72
RSUs granted	3,896		727		4,905		1,614
Weighted-average grant-date fair value of RSUs granted	$	4.73	$	16.48	$	4.98	$	17.98