Restructuring, Impairment and Other Costs of Terminated Program (Tables)

9 Months Ended

Sep. 30, 2022

Restructuring and Related Activities [Abstract]

Schedule of Restructuring, Impairment and Other Costs of Terminated Program

Restructuring, impairment and other costs of terminated program includes the following (in thousands):

	Three Months Ended		Nine Months Ended
	September 30, 2022
Clinical trial expense, other third-party and employee costs for the wind down of the bempegaldesleukin program	$	8,530	$	28,938
Severance and benefit expense	2,077		29,827
Impairment of right-of-use assets and property, plant and equipment	1,200		58,521
Contract termination and other restructuring costs	5,023		7,064
Restructuring, impairment and other costs of terminated program	$	16,830	$	124,350

The following table provides details regarding the severance and other termination benefit expense and a reconciliation of such liability for the three and nine months ended September 30, 2022, which we report within Accrued compensation on our Condensed Consolidated Balance Sheet (in thousands):

	Three and Nine Months Ended September 30, 2022
	No service period		Service period required		Total
Total severance and other termination benefits, at fair value	$	23,000	$	7,955	$	30,955
Liability balance as of March 31, 2022	$	—	$	—	$	—
Expense recognized during the period	23,588		4,162		27,750
Payments during the period	(12,881)		—		(12,881)
Liability balance as of June 30, 2022	$	10,707	$	4,162	$	14,869
Expense recognized during the period	(588)		2,661		2,073
Payments during the period	(9,544)		(2,505)		(12,049)
Liability balance as of September 30, 2022	$	575	$	4,318	$	4,893

Additionally, we recorded an impairment expense primarily for software which we plan to abandon and certain excess equipment based on the estimated income from selling such assets, which we also present as assets held for sale in other current assets in our Condensed Consolidated Balance Sheet as of September 30, 2022. We recorded impairment charges as follows (in thousands):

	Nine Months Ended September 30, 2022
	Property, Plant and Equipment		Operating Lease Right-of-Use Assets		Total
Net book value of impaired facilities before write-off	$	16,348	$	74,191	$	90,539
Less: Fair value of impaired facilities — Level 3 of Fair Value Hierarchy	(6,976)		(30,162)		(37,138)
Impairment expense for facilities	9,372		44,029		53,401
Impairment of other property, plant and equipment	5,120		—		5,120
Total impairment of right-of-use assets and property, plant and equipment	$	14,492	$	44,029	$	58,521

Schedule of Property, Plant and Equipment

The following table presents our property, plant and equipment as of September 30, 2022 and December 31, 2021, reflecting the effects of the impairment charges and held-for-sale reclassifications.

	September 30, 2022		December 31, 2021
Building and leasehold improvements	$	78,380	$	97,385
Laboratory equipment	34,628		42,704
Computer equipment and software	28,183		28,829
Manufacturing equipment	23,779		22,374
Furniture, fixtures, and other	4,647		10,094
Depreciable property, plant and equipment at cost	169,617		201,386
Less: accumulated depreciation	(135,064)		(148,039)
Depreciable property, plant and equipment, net	34,553		53,347
Construction-in-progress	2,250		7,163
Property, plant and equipment, net	$	36,803	$	60,510