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Cash and Investments in Marketable Securities (Tables)
 9 Months Ended
Sep. 30, 2022
Fair Value Disclosures [Abstract]  
Schedule of Cash and Investments in Marketable Securities, Including Cash Equivalents Cash and investments in marketable securities, including cash equivalents, are as follows (in thousands):
Estimated Fair Value at
September 30, 2022December 31, 2021
Cash and cash equivalents$105,758 $25,218 
Short-term investments440,629 708,737 
Long-term investments— 64,828 
Total cash and investments in marketable securities$546,387 $798,783 
Schedule of Portfolio of Cash and Investments in Marketable Securities Our portfolio of cash and investments in marketable securities includes (in thousands):
Fair Value Hierarchy LevelSeptember 30, 2022December 31, 2021
Amortized CostGross Unrealized GainsGross Unrealized LossesFair ValueFair Value
Corporate notes and bonds2$115,652 $— $(1,489)$114,163 $278,121 
Corporate commercial paper2358,066 — (1,763)356,303 478,629 
Obligations of U.S. government agencies21,130 — — 1,130 5,875 
Available-for-sale investments$474,848 $— $(3,252)$471,596 $762,625 
Money market funds150,696 23,968 
Certificates of deposit215,754 10,940 
CashN/A8,341 1,250 
Total cash and investments in marketable securities$546,387 $798,783