Operating Leases - Schedule of Operating Lease Information (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2021 USD ($) ft² term	Dec. 31, 2020 USD ($) ft²	Dec. 31, 2019 USD ($)
Leases [Line Items]
Operating lease right-of-use assets recognized in exchange for lease liabilities	$ 1,057	$ 2,133	$ 57,691
Mission Bay Facility
Leases [Line Items]
Leased space delivered (in sq ft) | ft²	2,012	4,940
Operating lease right-of-use assets recognized in exchange for lease liabilities	$ 1,057	$ 2,133
Number of consecutive terms to extend lease | term	2
Lease extension term	5 years
Third Street Facility
Leases [Line Items]
Leased space delivered (in sq ft) | ft²	0	0
Operating lease right-of-use assets recognized in exchange for lease liabilities	$ 0	$ 0
Number of consecutive terms to extend lease | term	1
Lease extension term	5 years