Liabilities Related to the Sales of Future Royalties (Tables)

12 Months Ended

Dec. 31, 2021

Liability Related To Sale Of Potential Future Royalties [Abstract]

Schedule of Liability Related to Potential Future Royalties

The following table shows the activity within the liability account of each arrangement (in thousands):

	Year-Ended December 31, 2021						Period from inception to December 31, 2021
	2012 Purchase and Sale Agreement		2020 Purchase and Sale Agreement		Total		2012 Purchase and Sale Agreement		2020 Purchase and Sale Agreement		Total
Liabilities related to the sales of future royalties—beginning balance	$	65,880	$	139,375	$	205,255	$	—	$	—	$	—
Royalty monetization proceeds	—		—		—		124,000		150,000		274,000
Non-cash royalty revenue	(37,578)		(40,168)		(77,746)		(282,658)		(50,793)		(333,451)
Non-cash interest expense	26,458		20,855		47,313		223,418		20,855		244,273
Payments to RPI	—		—		—		(10,000)		—		(10,000)
Loss on revaluation of liability related to the sale of future royalties	23,522				23,522		23,522		—		23,522
Liabilities related to the sales of future royalties – ending balance	78,282		120,062		198,344		78,282		120,062		198,344
Less: unamortized transaction costs	—		(2,917)		(2,917)		—		(2,917)		(2,917)
Liabilities related to the sales of future royalties, net	$	78,282	$	117,145	$	195,427	$	78,282	$	117,145	$	195,427