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Operating Leases
12 Months Ended
Dec. 31, 2021
Leases [Abstract]  
Operating Leases Operating Leases    Our leases consist of a Lease Agreement (the Mission Bay Lease) with ARE-San Francisco No. 19, LLC (ARE) for our 155,215 square foot corporate office and R&D facility located at 455 Mission Bay Boulevard, San Francisco, California (the Mission Bay Facility) and a Lease Agreement (the Third Street Lease) with Kilroy Realty Finance Partnership, L.P. (Kilroy) for an additional 135,936 square foot facility to support our R&D operations at 360 Third Street, San Francisco,
California (the Third Street Facility). The following table presents key information regarding these leases (dollars in thousands):
Mission Bay FacilityThird Street Facility
Lease commencementSeptember 2017June 2018
Lease termJanuary 2030January 2030
Space delivered during the year ended December 31, 2020
Square footage4,940 — 
Right-of-use asset and lease liability recognized$2,133 $— 
Space delivered during the year ended December 31, 2021
Square footage2,012 — 
Right-of-use asset and lease liability recognized$1,057 $— 
Renewal terms
Two consecutive five-year terms
One five-year term
The monthly base rent for both facilities will escalate over the term of the lease at various intervals.
Both leases include various covenants, indemnities, defaults, termination rights, security deposits and other provisions customary for lease transactions of this nature.
During the term of the Mission Bay Lease, we are responsible for paying our share of operating expenses specified in the lease, including utilities, common area maintenance, insurance costs and taxes.
For the Third Street Lease, our fixed annual base rent on an industrial gross lease basis includes certain expenses and property taxes paid directly by the landlord. We have a one-time right of first offer with respect to certain additional rental space at the Third Street Facility.
We recognize rent expense for these operating leases on a straight-line basis over the lease period. The components of lease expense, which we include in operating expenses in our Consolidated Statements of Operations, were as follows (in thousands):
Year Ended December 31,
202120202019
Operating lease expense$19,153 $18,985 $14,697 
Variable lease expense8,974 8,179 6,408 
Total lease expense$28,127 $27,164 $21,105 
    During the years ended December 31, 2021, 2020 and 2019, we paid $16.8 million, $16.2 million and $8.4 million, respectively, of operating lease payments related to our lease liabilities, which we include in net cash used in operating activities in our Consolidated Statements of Cash Flows.
As of December 31, 2021, the maturities of our operating lease liabilities were as follows (in thousands):
Year ending December 31,
2022$18,626 
202320,909 
202421,572 
202522,255 
202622,957 
2027 and thereafter75,411 
Total lease payments
181,730 
Less: portion representing interest
(37,900)
Less: lease incentives
(653)
Operating lease liabilities
143,177 
Less: current portion
(17,441)
Operating lease liabilities, less current portion
$125,736 
    As of December 31, 2021, the weighted-average remaining lease term is 8.1 years and the weighted-average discount rate used to determine the operating lease liability was 5.8%.