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Stock-Based Compensation (Tables)
9 Months Ended
Sep. 30, 2020
Share-based Payment Arrangement [Abstract]  
Stock-Based Compensation Expense
We recognized total stock-based compensation expense in our Condensed Consolidated Statements of Operations as follows (in thousands):
Three months ended September 30, Nine months ended September 30,
2020201920202019
Cost of goods sold
$744 $1,119 $2,168 $3,208 
Research and development
14,212 15,680 43,826 47,549 
General and administrative
8,711 8,081 25,255 24,030 
Impairment of assets and other costs for terminated program— — 1,025 — 
Total stock-based compensation
$23,667 $24,880 $72,274 $74,787 
Share-based Compensation, Activity
We issued stock-based awards and resulting shares of our common stock as follows (shares in thousands):
Three months ended September 30, Nine months ended September 30,
2020201920202019
Options granted
233 131 282 246 
Weighted-average grant-date fair value of options granted
$11.64 $13.43 $11.68 $15.81 
RSUs granted
693 316 1,213 712 
Weighted-average grant-date fair value of RSUs granted
$21.56 $28.00 $21.04 $31.80 
Shares issued under equity compensation plans
584 820 2,889 2,256