Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2020	Dec. 31, 2019
Current assets:
Cash and cash equivalents	$ 58,206	$ 96,363
Short-term investments	980,191	1,228,499
Accounts receivable	47,245	36,802
Inventory	12,584	12,665
Advance payments to contract manufacturers	15,972	31,834
Other current assets	37,770	15,387
Total current assets	1,151,968	1,421,550
Long-term investments	172,166	279,119
Property, plant and equipment, net	61,372	65,665
Operating lease right-of-use assets	131,458	134,177
Goodwill	76,501	76,501
Other assets	1,413	344
Total assets	1,594,878	1,977,356
Current liabilities:
Senior secured notes, net and interest payable (see Note 1)	0	252,891
Accounts payable	19,246	19,234
Accrued compensation	22,548	11,467
Accrued clinical trial expenses	42,794	32,626
Accrued contract manufacturing expenses	11,050	7,304
Other accrued expenses	11,424	12,338
Operating lease liabilities, current portion	15,139	12,516
Deferred revenue, current portion	1,757	5,517
Total current liabilities	123,958	353,893
Operating lease liabilities, less current portion	141,633	142,730
Liability related to the sale of future royalties, net	68,284	72,020
Deferred revenue, less current portion	2,524	2,554
Other long-term liabilities	2,239	768
Total liabilities	338,638	571,965
Commitments and contingencies
Stockholders’ equity:
Preferred stock, $0.0001 par value; 10,000 shares authorized; no shares designated or outstanding at June 30, 2020 or December 31, 2019	0	0
Common stock, $0.0001 par value; 300,000 shares authorized; 178,810 shares and 176,505 shares outstanding at June 30, 2020 and December 31, 2019, respectively	18	17
Capital in excess of par value	3,338,876	3,271,097
Accumulated other comprehensive income (loss)	715	(1,005)
Accumulated deficit	(2,083,369)	(1,864,718)
Total stockholders’ equity	1,256,240	1,405,391
Total liabilities and stockholders’ equity	$ 1,594,878	$ 1,977,356
Preferred stock, par value (in dollars per share)	$ 0.0001	$ 0.0001
Preferred stock, shares authorized (in shares)	10,000,000	10,000,000
Preferred stock, shares designated (in shares)	0	0
Preferred stock, shares outstanding (in shares)	0	0
Common stock, par value (in dollars per share)	$ 0.0001	$ 0.0001
Common stock, shares authorized (in shares)	300,000,000	300,000,000
Common stock, shares outstanding (in shares)	178,810,000	176,505,000