McGladrey & Pullen
Certified Public Accountants

Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

We consent to the incorporation by reference in this Registration Statement on Form S-3 of QCR Holdings, Inc. of our reports dated March 6, 2009, relating to our audits of the consolidated financial statements and internal control over financial reporting. We also consent to the reference to our firm under the caption “experts” in such prospectus.

/s/ McGladrey & Pullen, LLP

Davenport, Iowa
March 6, 2009

McGladrey & Pullen, LLP is a member firm of RSM International –
an affiliation of separate and independent legal entities.