SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

______________

SCHEDULE TO

Tender Offer Statement Under Section 14(d)(1) or 13(e)(1)

of the Securities Exchange Act of 1934

(Amendment No. 22)

______________

TARO PHARMACEUTICAL INDUSTRIES LTD.

(Name of Subject Company (Issuer))

______________

ALKALOIDA CHEMICAL COMPANY EXCLUSIVE GROUP LTD.

(Name of Filing Person (Offeror))

a subsidiary of

SUN PHARMACEUTICAL INDUSTRIES LTD.

ORDINARY SHARES, NOMINAL (PAR) VALUE NIS 0.0001 PER SHARE

(Title of Class of Securities)

M8737E108

(CUSIP Number of Class of Securities)

______________

Mr. Harin P. Mehta

Director

Alkaloida Chemical Company Exclusive Group Ltd.

Kabay János u. 29, H-4440 Tiszavasari, The Republic of Hungary

+36-42-521-005

(Name, Address and Telephone Number of Persons Authorized to Receive Notices

and Communications on Behalf of filing persons)

______________

Copy to:

Peter D. Lyons

Shearman & Sterling LLP

599 Lexington Avenue

New York, New York 10022

(212) 848-4000

Clifford M. J. Felig

Meitar Liquornik Geva & Leshem Brandwein

16 Abba Hillel Silver Rd.

Ramat Gan 52506, Israel

(972) 3-610-3100

CALCULATION OF FILING FEE

Transaction Valuation*	Amount of Filing Fee**

$194,554,682.50	$7,646.00

*	Estimated for purposes of calculating the amount of the filing fee only. Calculated by multiplying $7.75, the per share tender offer price, by 25,103,830 shares.
**	Calculated as 0.00393% of the transaction value.
R	Check the box if any part of the fee is offset as provided by Rule 0-11(a)(2) and identify the filing with which the offsetting fee was previously paid. Identify the previous filing by registration statement number, or the Form or Schedule and the date of its filing.
	Amount Previously Paid: $7,800.00	Filing Party: Alkaloida Chemical Company Exclusive Group Ltd.
	Form or Registration No.: Schedule TO	Date Filed: June 30, 2008
£	Check the box if the filing relates solely to preliminary communications made before the commencement of a tender offer.
	Check the appropriate boxes to designate any transactions to which the statement relates:
R	third-party tender offer subject to Rule 14d-1.
£	issuer tender offer subject to Rule 13e-4.
£	going-private transaction subject to Rule 13e-3.
£	amendment to Schedule 13D under Rule 13d-2.
	Check the following box if the filing is a final amendment reporting the results of the tender offer: £

This Amendment No. 22 (this “Amendment”) amends and supplements the Tender Offer Statement on Schedule TO filed on June 30, 2008, as amended by Amendment No. 1, Amendment No. 2, Amendment No. 3, Amendment No. 4, Amendment No. 5, Amendment No. 6, Amendment No. 7, Amendment No. 8, Amendment No. 9, Amendment No. 10, Amendment No. 11, Amendment No. 12, Amendment No. 13, Amendment No. 14, Amendment No. 15, Amendment No. 16, Amendment No. 17, Amendment No. 18, Amendment No. 19, Amendment No. 20 and Amendment No. 21 (as so amended, the “Schedule TO”) by Alkaloida Chemical Company Exclusive Group Ltd. (“Purchaser”), a Hungarian company and a subsidiary of Sun Pharmaceutical Industries Ltd. (“Sun”), an Indian company. This Schedule TO relates to the offer by Purchaser to purchase all outstanding Ordinary Shares, nominal (par) value NIS 0.0001 per share, of Taro Pharmaceutical Industries Ltd. (the “Company”), an Israeli corporation, at a purchase price of $7.75 per Ordinary Share, net to the seller in cash (subject to applicable withholding taxes), without interest, upon the terms and subject to the conditions set forth in the Offer to Purchase dated June 30, 2008 and in the related Letter of Transmittal. Except as specifically provided herein, this Amendment does not modify any of the information previously reported on the Schedule TO.

Item 1.

Summary Term Sheet.

Item 1 of Schedule TO is hereby amended and supplemented as follows:

The response to the question “Can the Offer Be Extended, and Under What Circumstances?” in the “Summary Term Sheet” of the Offer to Purchase is hereby amended and restated in its entirety as follows:

“We may, without the consent of the Company, but subject to applicable law, extend the period of time during which the Initial Offering Period remains open. We may extend the Offer if the conditions to the Offer have not been satisfied or, to the extent permitted by applicable law, waived by us. In addition, after the expiration of the Initial Offering Period, we will provide a subsequent offering period of not less than ten business days nor more than 20 business days. You will not have withdrawal rights during the subsequent offering period. See Section 1.”

The response to the question “How Will I Be Notified If the Offer Is Extended?” in the “Summary Term Sheet” of the Offer to Purchase is hereby amended and restated in its entirety as follows:

“If we decide to extend the Offer, and upon the commencement of the subsequent offering period, we will inform Computershare, the Depositary, of that fact, and will issue a press release giving the new expiration date no later than 9:00 a.m., New York City time, on the next business day after the day on which the Initial Offering Period was previously scheduled to expire. See Section 1.”

Item 4.

Terms of the Transaction.

Item 4 of Schedule TO is hereby amended and supplemented as follows:

The “Introduction” of the Offer to Purchase is hereby amended and supplemented as follows:

The last paragraph of the “Introduction,” entitled “Subsequent Offering Period,” is hereby amended and restated in its entirety as follows:

“Subsequent Offering Period. Purchaser will provide for a subsequent offering period of not less than ten business days nor more than 20 business days. Purchaser will make a public announcement of the results of the Offer during the Initial Offering Period no later than 9:00 a.m., New York City time, on the next business day after the expiration of the Initial Offering Period and will immediately begin the subsequent offering period. See Section 1.”

Section 1 of the Offer to Purchase entitled “Terms of the Offer; Expiration Date” is hereby amended and supplemented as follows:

The following paragraph is hereby added to the end of the fourteenth paragraph of Section 1 of the Offer to Purchase:

“Sun announced that Purchaser will make a public announcement promptly after the Supreme Court of Israel issues a ruling on the appeal of the STO Litigation or if, prior to such ruling, the Temporary Order is otherwise lifted (the “Announcement Date”). Sun further announced that Purchaser had extended the Expiration Date of the Offer to 12:00 midnight, New York City time, on the fifth business day following the Announcement Date. The Offer had previously been scheduled to expire at 5:00 p.m., New York City time, on Friday, April 24, 2009. As of 5:00 p.m., New York City time, on April 23, 2009, 31,067 Ordinary Shares had been tendered and not withdrawn from the Offer. Purchaser expressly reserves the right to further extend the Offer if the conditions of the Offer have not been satisfied or, to the extent permitted by applicable law, waived by Purchaser as of the Expiration Date.”

The antepenultimate paragraph of Section 1 of the Offer to Purchase, beginning with the words “Although Purchaser does not currently intend to do so,” is hereby amended and restated in its entirety as follows:

“Purchaser will provide a subsequent offering period of not less than ten business days nor more than 20 business days (the “Subsequent Offering Period”) following the expiration of the Initial Offering Period, if, among other things, upon the Expiration Date (i) all of the conditions to Purchaser’s obligations to accept for payment, and to pay for, the Ordinary Shares validly tendered (and not withdrawn in accordance with the procedures set forth in Section 4) are satisfied or waived by Purchaser, and (ii) Purchaser immediately accepts for payment, and promptly pays for, all Ordinary Shares validly tendered and not withdrawn prior to the Expiration Date. Ordinary Shares tendered during the Subsequent Offering Period may not be withdrawn. See Section 4. Purchaser will immediately accept for payment, and promptly pay for, all validly tendered Ordinary Shares as they are received during the Subsequent Offering Period. The election by Purchaser to provide a Subsequent Offering Period will be effected by

Purchaser giving oral or written notice of the Subsequent Offering Period to the Depositary. Purchaser will announce the results of the Initial Offering Period by issuing a press release to the Dow Jones News Service or the Public Relations Newswire no later than 9:00 a.m. Eastern time on the next business day after the Expiration Date and will immediately begin the Subsequent Offering Period.”

All occurrences of qualifying language in the Offer to Purchase to the effect of “If Purchaser decides to provide a Subsequent Offering Period” are hereby deleted.

The press release issued by Sun announcing that Purchaser had extended the Offer is attached hereto as Exhibit (a)(5)(T).

Item 12.

Exhibits.

Item 12 of the Schedule TO is hereby amended and restated as follows:

(a)(1)(A)

Offer to Purchase dated June 30, 2008.*

(a)(1)(B)

Form of Letter of Transmittal.*

(a)(1)(C)

Form of Notice of Guaranteed Delivery.*

(a)(1)(D)

Form of Letter to Brokers, Dealers, Commercial Banks, Trust Companies and Other Nominees.*

(a)(1)(E)

Form of Letter to Clients for use by Brokers, Dealers, Commercial Banks, Trust Companies and Other Nominees.*

(a)(1)(F)

Guidelines for Certification of Taxpayer Identification Number on Substitute Form W-9.*

(a)(1)(G)

Declaration Form (“Declaration of Status for Israeli Income Tax Purposes”).*

(a)(5)(A)

Summary Advertisement as published in The Wall Street Journal on June 30, 2008.*

(a)(5)(B)

*	Previously filed.

Original Schedule 13D, filed on May 29, 2008 (the “Amendment No. 4”); the Amendment No. 5 to the Original Schedule 13D, filed on June 5, 2008 (the “Amendment No. 5”); the Amendment No. 6 to the Original Schedule 13D, filed on June 24, 2008; the Amendment No. 7 to the Original Schedule 13D, filed on June 25, 2008 (the “Amendment No. 7”, together with the Original Schedule 13D, the Amendment No. 1, the Amendment No. 2, the Amendment No. 3, the Amendment No. 4, the Amendment No. 5 and the Amendment No. 6, the “Schedule 13D”) and by reference to Statement on Schedule TO filed by Purchaser on June 25, 2008.*

(a)(5)(C)

Text of Press Release issued by Purchaser on June 30, 2008.*

(a)(5)(D)

Text of Press Release issued by Purchaser on July 14, 2008.*

(a)(5)(E)

Text of Press Release issued by Sun on July 30, 2008.*

(a)(5)(F)

Text of Press Release issued by Sun on August 13, 2008.*

(a)(5)(G)

Text of Press Release issued by Sun on August 27, 2008.*

(a)(5)(H)

Text of Press Release issued by Sun on August 27, 2008.*

(a)(5)(I)

Text of Press Release issued by Sun on September 3, 2008.*

(a)(5)(J)

Text of Press Release issued by Sun on October 3, 2008.*

(a)(5)(K)

Text of Press Release issued by Sun on November 7, 2008.*

(a)(5)(L)

Text of Press Release issued by Sun on December 19, 2008.*

(a)(5)(M)

Text of letter from Sun’s Chairman and Managing Director, Dilip Shanghvi, to Myron Strober, Chairman of the Audit Committee of the Board of Directors of the Company, dated January 2, 2009, regarding the financial statements of the Company.*

(a)(5)(N)

Text of Press Release issued by Sun on January 7, 2009.*

(a)(5)(O)

Text of Press Release issued by Sun on January 29, 2009.*

(a)(5)(P)

Text of Press Release issued by Sun on March 6, 2009.*

(a)(5)(Q)

Text of Press Release issued by Sun on March 20, 2009.*

(a)(5)(R)

Text of Press Release issued by Sun on April 3, 2009.*

(a)(5)(S)

Text of Press Release issued by Sun on April 17, 2009.*

(a)(5)(T)

Text of Press Release issued by Sun on April 24, 2009.

(b)	Not applicable.

(d)(A)

Agreement of Merger, dated as of May 18, 2007, among Purchaser, Aditya Acquisition Company Ltd. and the Company, incorporated by reference to the Schedule 13D.*

(d)(B)

Amendment No. 1 to Agreement of Merger, dated as of July 23, 2007, among Purchaser, Aditya Acquisition Company Ltd. and the Company, incorporated by reference to the Schedule 13D.*

(d)(C)

Option Letter Agreement, dated as of May 18, 2007, among Taro Development Corporation, Barrie Levitt, Tal Levitt, Daniel Moros, Jacob Levitt and Purchaser, incorporated by reference to the Schedule 13D.*

(d)(D)

Share Purchase Agreement, dated as of May 18, 2007, among Purchaser and the Company, incorporated by reference to the Schedule 13D.*

(d)(E)

Agreement and Plan of Merger, dated as of May 18, 2007, among Sun Pharmaceutical Industries, Inc., Sun Development Corporation I, Taro Development Corporation, Barrie Levitt and Daniel Moros, incorporated by reference to the Schedule 13D.*

(d)(F)

Voting Agreement, dated as of May 18, 2007, between Purchaser and Barrie Levitt.*

(d)(G)

Voting Agreement, dated as of May 18, 2007, between Purchaser and Daniel Moros.*

(d)(H)

Voting Agreement, dated as of May 18, 2007, between Purchaser and Tal Levitt.*

(d)(I)

Voting Agreement, dated as of May 18, 2007, between Purchaser and Taro Development Corporation.*

(d)(J)

Voting Agreement, dated as of May 18, 2007, between Purchaser and Morley & Company, Inc.*

(d)(K)

Voting Agreement, dated as of May 18, 2007, between Sun Pharmaceutical Industries, Inc. and Barrie Levitt.*

(d)(L)

Voting Agreement, dated as of May 18, 2007, between Sun Pharmaceutical Industries, Inc. and Daniel Moros.*

(d)(M)

Voting Agreement, dated as of May 18, 2007, between Sun Pharmaceutical Industries, Inc. and Tal Levitt.*

(d)(N)

Voting Agreement, dated as of May 18, 2007, between Sun Pharmaceutical Industries, Inc. and Jacob Levitt.*

(d)(O)

Warrant, dated as of May 18, 2007, issued by the Company to Sun, incorporated by reference to the Schedule 13D.*

(d)(P)

Warrant No. 2, dated as of August 1, 2007, issued by the Company to Sun, incorporated by reference to the Schedule 13D.*

(d)(Q)

Registration Rights Agreement, dated as of May 18, 2007, between the Company and Purchaser, incorporated by reference to the Schedule 13D.*

(d)(R)

Assignment and Assumption Agreement, dated as of June 24, 2008, between Purchaser and Sun, incorporated by reference to Schedule 13D.*

(d)(S)

Irrevocable Trust Agreement, dated as of June 29, 2008, between Purchaser and Ubank Trust Company Ltd.*

(d)(T)

A letter of demand for delivery pursuant to the Option Agreement, dated August 27, 2008, from Purchaser to Taro Development Corporation, Barrie Levitt, Tal Levitt, Jacob Levitt and Daniel Moros.*

(d)(U)

A letter from Sun’s Chairman and Managing Director, Dilip Shanghvi, to the Company’s Board of Directors, dated January 2, 2009, regarding proposed settlement terms for the STO Litigation.*

(d)(V)

A letter from Sun’s Chairman and Managing Director, Dilip Shanghvi, to the Company’s Board of Directors, dated January 7, 2009, in response to the letters from Dr. Levitt, dated January 4 and January 6, 2009.*

(g)	Not applicable.

(h)	Not applicable.

After due inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Dated: April 24, 2009

ALKALOIDA CHEMICAL COMPANY EXCLUSIVE GROUP LTD.


By:	/s/ Harin Mehta
	Name:	Mr. Harin Mehta
	Title:	Director

After due inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Dated: April 24, 2009

SUN PHARMACEUTICAL INDUSTRIES LTD.


By:	/s/ Sudhir V. Valia
	Name:	Mr. Sudhir V. Valia
	Title:	Director

EXHIBIT INDEX

Exhibit

No.

(a)(1)(A)

Offer to Purchase dated June 30, 2008.*

(a)(1)(B)

Form of Letter of Transmittal.*

(a)(1)(C)

Form of Notice of Guaranteed Delivery.*

(a)(1)(D)

Form of Letter to Brokers, Dealers, Commercial Banks, Trust Companies and Other Nominees.*

(a)(1)(E)

Form of Letter to Clients for use by Brokers, Dealers, Commercial Banks, Trust Companies and Other Nominees.*

(a)(1)(F)

Guidelines for Certification of Taxpayer Identification Number on Substitute Form W-9.*

(a)(1)(G)

Declaration Form (“Declaration of Status for Israeli Income Tax Purposes”).*

(a)(5)(A)

Summary Advertisement as published in The Wall Street Journal on June 30, 2008.*

(a)(5)(B)

Text of Press Release issued by Sun on June 25, 2008, incorporated by reference to the Statement on Schedule 13D (including exhibits), originally filed by Sun, Sun Pharma Global Inc. and Purchaser, with respect to the Ordinary Shares, par value NIS 0.0001 per share of the Company, with the U.S. Securities and Exchange Commission (the “Original Schedule 13D”); the Amendment No. 1 to the Original Schedule 13D, filed on July 25, 2007 (the “Amendment No. 1”); the Amendment No. 2 to the Original Schedule 13D, filed on August 2, 2007 (the “Amendment No. 2”); the Amendment No. 3 to the Original Schedule 13D, filed on February 19, 2008 (the “Amendment No. 3”); the Amendment No. 4 to the Original Schedule 13D, filed on May 29, 2008 (the “Amendment No. 4”); the Amendment No. 5 to the Original Schedule 13D, filed on June 5, 2008 (the “Amendment No. 5”); the Amendment No. 6 to the Original Schedule 13D, filed on June 24, 2008; the Amendment No. 7 to the Original Schedule 13D, filed on June 25, 2008 (the “Amendment No. 7”, together with the Original Schedule 13D, the Amendment No. 1, the Amendment No. 2, the Amendment No. 3, the Amendment No. 4, the Amendment No. 5 and the Amendment No. 6, the “Schedule 13D”) and by reference to Statement on Schedule TO filed by Purchaser on June 25, 2008.*

(a)(5)(C)

Text of Press Release issued by Purchaser on June 30, 2008.*

*	Previously filed.

(a)(5)(D)

Text of Press Release issued by Purchaser on July 14, 2008.*

(a)(5)(E)

Text of Press Release issued by Sun on July 30, 2008.*

(a)(5)(F)

Text of Press Release issued by Sun on August 13, 2008.*

(a)(5)(G)

Text of Press Release issued by Sun on August 27, 2008.*

(a)(5)(H)

Text of Press Release issued by Sun on August 27, 2008.*

(a)(5)(I)

Text of Press Release issued by Sun on September 3, 2008.*

(a)(5)(J)

Text of Press Release issued by Sun on October 3, 2008.*

(a)(5)(K)

Text of Press Release issued by Sun on November 7, 2008.*

(a)(5)(L)

Text of Press Release issued by Sun on December 19, 2008.*

(a)(5)(M)

(a)(5)(N)

Text of Press Release issued by Sun on January 7, 2009.*

(a)(5)(O)

Text of Press Release issued by Sun on January 29, 2009.*

(a)(5)(P)

Text of Press Release issued by Sun on March 6, 2009.*

(a)(5)(Q)

Text of Press Release issued by Sun on March 20, 2009.*

(a)(5)(R)

Text of Press Release issued by Sun on April 3, 2009.*

(a)(5)(S)

Text of Press Release issued by Sun on April 17, 2009.*

(a)(5)(T)

Text of Press Release issued by Sun on April 24, 2009.

(b)	Not applicable.

(d)(A)

Agreement of Merger, dated as of May 18, 2007, among Purchaser, Aditya Acquisition Company Ltd. and the Company, incorporated by reference to the Schedule 13D.*

(d)(B)

Amendment No. 1 to Agreement of Merger, dated as of July 23, 2007, among Purchaser, Aditya Acquisition Company Ltd. and the Company, incorporated by reference to the Schedule 13D.*

(d)(C)

(d)(D)

Share Purchase Agreement, dated as of May 18, 2007, among Purchaser and the Company, incorporated by reference to the Schedule 13D.*

(d)(E)

(d)(F)

Voting Agreement, dated as of May 18, 2007, between Purchaser and Barrie Levitt.*

(d)(G)

Voting Agreement, dated as of May 18, 2007, between Purchaser and Daniel Moros.*

(d)(H)

Voting Agreement, dated as of May 18, 2007, between Purchaser and Tal Levitt.*

(d)(I)

Voting Agreement, dated as of May 18, 2007, between Purchaser and Taro Development Corporation.*

(d)(J)

Voting Agreement, dated as of May 18, 2007, between Purchaser and Morley & Company, Inc.*

(d)(K)

Voting Agreement, dated as of May 18, 2007, between Sun Pharmaceutical Industries, Inc. and Barrie Levitt.*

(d)(L)

Voting Agreement, dated as of May 18, 2007, between Sun Pharmaceutical Industries, Inc. and Daniel Moros.*

(d)(M)

Voting Agreement, dated as of May 18, 2007, between Sun Pharmaceutical Industries, Inc. and Tal Levitt.*

(d)(N)

Voting Agreement, dated as of May 18, 2007, between Sun Pharmaceutical Industries, Inc. and Jacob Levitt.*

(d)(O)

Warrant, dated as of May 18, 2007, issued by the Company to Sun, incorporated by reference to the Schedule 13D.*

(d)(P)

Warrant No. 2, dated as of August 1, 2007, issued by the Company to Sun, incorporated by reference to the Schedule 13D.*

(d)(Q)

Registration Rights Agreement, dated as of May 18, 2007, between the Company and Purchaser, incorporated by reference to the Schedule 13D.*

(d)(R)

Assignment and Assumption Agreement, dated as of June 24, 2008, between Purchaser and Sun, incorporated by reference to Schedule 13D.*

(d)(S)

Irrevocable Trust Agreement, dated as of June 29, 2008, between Purchaser and Ubank Trust Company Ltd.*

(d)(T)

A letter of demand for delivery pursuant to the Option Agreement, dated August 27, 2008, from Purchaser to Taro Development Corporation, Barrie Levitt, Tal Levitt, Jacob Levitt and Daniel Moros.*

(d)(U)

A letter from Sun’s Chairman and Managing Director, Dilip Shanghvi, to the Company’s Board of Directors, dated January 2, 2009, regarding proposed settlement terms for the STO Litigation.*

(d)(V)

(g)	Not applicable.

(h)	Not applicable.