X0202 4 2005-06-17 0 0000834306 BIOSITE INC BSTE 0000903574 GREENE HOWARD E JR BIOSITE INCORPORATED 11030 ROSELLE STREET SAN DIEGO CA 92121 1 0 0 0 Non-Qualified Stock Option (right to buy) 53.38 2005-06-17 4 A 0 5000 0 A 2015-06-17 Common Stock 5000 5000 D Option vests in sixteen equal quarterly installments over four years (on each quarterly anniversary of the applicable vesting commencement date), provided that no shares may be exercised during the first six (6) month period following the commencement of vesting. By: Robyn Shutak For: Howard E. Greene, Jr. 2005-06-17