X0202 4 2004-06-15 0 0000822206 EPIMMUNE INC EPMN 0000903574 GREENE HOWARD E JR 5820 NANCY RIDGE DRIVE SAN DIEGO CA 92121 1 0 0 0 Non-Qualified Stock Option 1.92 2004-06-15 4 A 0 5000 0 A 2004-07-15 2014-06-15 Common Stock 5000 5000 D Grant to reporting person of a non-qualified stock option to purchase common stock pursuant to the terms of the Epimmune Inc. 2000 Stock Plan. The option vests in twelve (12) equal installments over one year from 06/15/2004, the date of Epimmune Inc.'s 2004 annual meeting of shareholders. The first installment vests and is exercisable on 07/15/2004, and the option will be fully vested on 06/15/2005. Robert J. De Vaere, CFO, by power of attorney 2004-06-15