The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2U INC COM USD0.001 | COM | 90214J101 | 143,713 | 3,753,270 | SH | DFND | 876,694 | 0 | 2,876,576 | ||
| AAC HLDGS INC COM | COM | 000307108 | 11,666 | 670,869 | SH | DFND | 70,864 | 0 | 600,005 | ||
| ABIOMED INC | COM | 003654100 | 1,064 | 8,272 | SH | DFND | 1,988 | 0 | 6,284 | ||
| ABLYNX N.V. NPV ISIN #BE0003877942 SEDOL #B28W603 | COM | B0031S109 | 183 | 14,574 | SH | DFND | 3,098 | 0 | 11,476 | ||
| ABRAXAS PETE CORP | COM | 003830106 | 885 | 523,689 | SH | DFND | 48,644 | 0 | 475,045 | ||
| ACACIA COMMUNICATIONS INC COM | COM | 00401C108 | 15,289 | 148,034 | SH | DFND | 5,718 | 0 | 142,316 | ||
| ACADIA HEALTHCARE COMPANY INC COM | COM | 00404A109 | 67,382 | 1,359,870 | SH | DFND | 209,959 | 0 | 1,149,911 | ||
| ACADIA PHARMACEUTICALS INC COM | COM | 004225108 | 179 | 5,629 | SH | DFND | 1,058 | 0 | 4,571 | ||
| ACCENTURE PLC CLS A USD0.0000225 | COM | G1151C101 | 872 | 7,135 | SH | DFND | 1,623 | 0 | 5,512 | ||
| ACTIVISION BLIZZARD INC COM | COM | 00507V109 | 92,144 | 2,079,992 | SH | DFND | 365,174 | 0 | 1,714,818 | ||
| ADESTO TECHNOLOGIES CORP COM | COM | 00687D101 | 3,689 | 1,661,907 | SH | DFND | 132,281 | 0 | 1,529,626 | ||
| ADIDAS AG NPV (REGD) ISIN #DE000A1EWWW0 SEDOL #4031976 | COM | D0066B185 | 23,563 | 135,449 | SH | DFND | 53,887 | 0 | 81,562 | ||
| ADOBE SYS INC | COM | 00724F101 | 46,948 | 432,538 | SH | DFND | 103,288 | 0 | 329,250 | ||
| ADVANCED MICRO DEVICES INC COM | COM | 007903107 | 193 | 27,924 | SH | DFND | 2,602 | 0 | 25,322 | ||
| ADVERUM BIOTECHNOLOGIES INC COM | COM | 00773U108 | 209 | 50,876 | SH | DFND | 20,510 | 0 | 30,366 | ||
| ALIBABA GROUP HLDG LTD | COM | 01609W102 | 29,365 | 277,579 | SH | DFND | 99,144 | 0 | 178,435 | ||
| ALIGN TECHNOLOGY INC COM | COM | 016255101 | 84,152 | 897,621 | SH | DFND | 161,698 | 0 | 735,923 | ||
| ALLEGIANT TRAVEL CO COM | COM | 01748X102 | 17,013 | 128,817 | SH | DFND | 9,706 | 0 | 119,111 | ||
| ALLERGAN PLC. COM USD0.0001 | COM | G0177J108 | 5,482 | 23,804 | SH | DFND | 606 | 0 | 23,198 | ||
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 92,293 | 1,361,656 | SH | DFND | 301,792 | 0 | 1,059,864 | ||
| ALPHABET INC CAP STK CL A | COM | 02079K305 | 40,001 | 49,749 | SH | DFND | 4,893 | 0 | 44,856 | ||
| ALPHABET INC CAP STK CL C | COM | 02079K107 | 82,799 | 106,523 | SH | DFND | 19,276 | 0 | 87,247 | ||
| AMAZON.COM INC | COM | 023135106 | 528,969 | 631,748 | SH | DFND | 219,844 | 0 | 411,904 | ||
| AMBARELLA INC COM USD0.00045 | COM | G037AX101 | 5,465 | 74,236 | SH | DFND | 12,219 | 0 | 62,017 | ||
| AMBER ROAD INC COM USD0.001 | COM | 02318Y108 | 720 | 74,573 | SH | DFND | 7,099 | 0 | 67,474 | ||
| AMEDISYS INC COM | COM | 023436108 | 42,527 | 896,437 | SH | DFND | 405,281 | 0 | 491,156 | ||
| AMERICAN INTL GROUP INC COM NEW | COM | 026874784 | 196 | 3,303 | SH | DFND | 91 | 0 | 3,212 | ||
| AMERICAN TOWER CORPORATION | COM | 03027X100 | 10,590 | 93,442 | SH | DFND | 7,562 | 0 | 85,880 | ||
| APACHE CORP | COM | 037411105 | 124,773 | 1,953,545 | SH | DFND | 306,208 | 0 | 1,647,337 | ||
| APPLE INC | COM | 037833100 | 3,535 | 31,269 | SH | DFND | 8,382 | 0 | 22,887 | ||
| APPLIED OPTOELECTRONICS INC COM | COM | 03823U102 | 9,357 | 421,296 | SH | DFND | 57,118 | 0 | 364,178 | ||
| APPTIO INC CL A | COM | 03835C108 | 2,169 | 99,947 | SH | DFND | 252 | 0 | 99,695 | ||
| ARISTA NETWORKS INC COM USD0.0001 | COM | 040413106 | 63,516 | 746,540 | SH | DFND | 36,256 | 0 | 710,284 | ||
| AT HOME GROUP INC COM | COM | 04650Y100 | 6,341 | 418,543 | SH | DFND | 24,959 | 0 | 393,584 | ||
| ATHENAHEALTH INC DELAWARE | COM | 04685W103 | 1,940 | 15,380 | SH | DFND | 3,511 | 0 | 11,869 | ||
| ATLASSIAN CORPORATION PLC COM USD0.1 CL A | COM | G06242104 | 15,720 | 524,515 | SH | DFND | 70,265 | 0 | 454,250 | ||
| AUTO TRADER GROUP PLC ORD GBP0.01 ISIN #GB00BVYVFW23 SEDOL #BVYV | COM | G06708104 | 10,765 | 2,043,635 | SH | DFND | 254,254 | 0 | 1,789,381 | ||
| AXIS BANK GDR EACH REPR 1 INR10 REG S ISIN #US05462W1099 SEDOL # | COM | 05462W109 | 1,500 | 37,310 | SH | DFND | 33,556 | 0 | 3,754 | ||
| BAIDU INC SPON ADR REP A | COM | 056752108 | 19,282 | 105,907 | SH | DFND | 61,768 | 0 | 44,139 | ||
| BANCO MACRO S.A. ADR REP 10 CLS B SHS ARS1 | COM | 05961W105 | 91 | 1,167 | SH | DFND | 224 | 0 | 943 | ||
| BARNES &NOBLE INC COM | COM | 067774109 | 88 | 7,781 | SH | DFND | 1,491 | 0 | 6,290 | ||
| BARRICK GOLD CORP COM NPV ISIN #CA0679011084 SEDOL #2024644 | COM | 067901108 | 30 | 1,666 | SH | DFND | 287 | 0 | 1,379 | ||
| BELLATRIX EXPLORATION LTD COM ISIN #CA0783141017 SEDOL #B580BW5 | COM | 078314101 | 743 | 869,821 | SH | DFND | 112,471 | 0 | 757,350 | ||
| BERKLEY W R CORP | COM | 084423102 | 3,971 | 68,742 | SH | DFND | 16,957 | 0 | 51,785 | ||
| BERKSHIRE HATHAWAY INC DEL CL B NEW | COM | 084670702 | 29 | 200 | SH | DFND | 0 | 0 | 200 | ||
| BIOGEN INC COM | COM | 09062X103 | 55 | 177 | SH | DFND | 4 | 0 | 173 | ||
| BIOMARIN PHARMACEUTICAL INC | COM | 09061G101 | 41,052 | 443,706 | SH | DFND | 172,821 | 0 | 270,885 | ||
| BMC STK HLDGS INC COM | COM | 05591B109 | 30,278 | 1,707,753 | SH | DFND | 207,541 | 0 | 1,500,212 | ||
| BOINGO WIRELESS INC COM USD0.0001 | COM | 09739C102 | 22,453 | 2,184,157 | SH | DFND | 328,593 | 0 | 1,855,564 | ||
| BOSTON SCIENTIFIC CORP | COM | 101137107 | 1,123 | 47,178 | SH | DFND | 20,722 | 0 | 26,456 | ||
| BOVIE MEDICAL CORP COM | COM | 10211F100 | 276 | 52,995 | SH | DFND | 255 | 0 | 52,740 | ||
| BOX INC CL A | COM | 10316T104 | 257 | 16,319 | SH | DFND | 2,161 | 0 | 14,158 | ||
| BRIGHTCOVE INC COM USD0.001 | COM | 10921T101 | 7,841 | 600,836 | SH | DFND | 120,545 | 0 | 480,291 | ||
| BUILDERS FIRSTSOURCE INC COM | COM | 12008R107 | 1,099 | 95,500 | SH | DFND | 34,048 | 0 | 61,452 | ||
| CARROLS RESTAURANT GROUP INC COM | COM | 14574X104 | 11,757 | 889,995 | SH | DFND | 80,358 | 0 | 809,637 | ||
| CATABASIS PHARMACEUTICALS INC COM | COM | 14875P107 | 138 | 22,445 | SH | DFND | 5,534 | 0 | 16,911 | ||
| CATAPULT GROUP INTL LTD ISIN #AU000000CAT9 SEDOL #BTL0Y76 | COM | Q2159P101 | 38,102 | 14,390,317 | SH | DFND | 2,870,747 | 0 | 11,519,570 | ||
| CBS CORP NEW CL B | COM | 124857202 | 1,642 | 29,998 | SH | DFND | 7,321 | 0 | 22,677 | ||
| CHARTER COMMUNICATIONS INC NEW CL A | COM | 16119P108 | 167 | 620 | SH | DFND | 26 | 0 | 594 | ||
| CHEGG INC COM USD0.001 | COM | 163092109 | 105 | 14,756 | SH | DFND | 10,651 | 0 | 4,105 | ||
| CHIPOTLE MEXICAN GRILL INC COM | COM | 169656105 | 53 | 124 | SH | DFND | 124 | 0 | 0 | ||
| COGENT COMMUNICATION HLDGS INC COM NEW | COM | 19239V302 | 261 | 7,090 | SH | DFND | 667 | 0 | 6,423 | ||
| CONNS INC COM | COM | 208242107 | 614 | 59,469 | SH | DFND | 40 | 0 | 59,429 | ||
| CONSTELLATION BRANDS INC CL A | COM | 21036P108 | 5,590 | 33,575 | SH | DFND | 825 | 0 | 32,750 | ||
| CORBUS PHARMACEUTICALS HLDGS COM | COM | 21833P103 | 508 | 74,860 | SH | DFND | 23,325 | 0 | 51,535 | ||
| COSTAR GROUP INC COM | COM | 22160N109 | 17,506 | 80,847 | SH | DFND | 10,257 | 0 | 70,590 | ||
| CTRIP.COM INTERNATIONAL LTD ADS EACH REP 0.125 ORD USD0.01 | COM | 22943F100 | 2,959 | 63,548 | SH | DFND | 13,450 | 0 | 50,098 | ||
| DELTA AIR LINES INC DEL COM NEW | COM | 247361702 | 6,411 | 162,886 | SH | DFND | 4,618 | 0 | 158,268 | ||
| DEXCOM INC | COM | 252131107 | 61,243 | 698,642 | SH | DFND | 172,579 | 0 | 526,063 | ||
| DIPLOMAT PHARMACY INC COM | COM | 25456K101 | 2,235 | 79,803 | SH | DFND | 20,665 | 0 | 59,138 | ||
| DIRTT ENVIRONMENTAL SOLUT LTD COM ISIN #CA25490H1064 SEDOL #BH13 | COM | 25490H106 | 40,322 | 10,641,075 | SH | DFND | 609,015 | 0 | 10,032,060 | ||
| E L F BEAUTY INC COM | COM | 26856L103 | 20,623 | 733,395 | SH | DFND | 226,489 | 0 | 506,906 | ||
| ECO STIM ENERGY SOLUTIONS INC COM | COM | 27888D101 | 2,131 | 996,020 | SH | DFND | 70,475 | 0 | 925,545 | ||
| ECOSYNTHETIX INC COM ISIN #CA27923D1087 SEDOL #B4XBZ35 | COM | 27923D108 | 83 | 48,218 | SH | DFND | 3,983 | 0 | 44,235 | ||
| EDWARDS LIFESCIENCES CORP | COM | 28176E108 | 777 | 6,444 | SH | DFND | 1,151 | 0 | 5,293 | ||
| ELECTRONIC ARTS | COM | 285512109 | 30,989 | 362,863 | SH | DFND | 61,210 | 0 | 301,653 | ||
| ELLIE MAE INC COM USD0.0001 | COM | 28849P100 | 460 | 4,372 | SH | DFND | 2,597 | 0 | 1,775 | ||
| ENPHASE ENERGY INC COM USD0.00001 | COM | 29355A107 | 45 | 37,756 | SH | DFND | 7,029 | 0 | 30,727 | ||
| ENZO BIOCHEM INC | COM | 294100102 | 4,439 | 872,009 | SH | DFND | 215,362 | 0 | 656,647 | ||
| EPAM SYS INC COM USD0.001 | COM | 29414B104 | 71,571 | 1,032,625 | SH | DFND | 163,727 | 0 | 868,898 | ||
| ESPERION THERAPEUTICS INC COM USD0.001 | COM | 29664W105 | 52 | 3,761 | SH | DFND | 373 | 0 | 3,388 | ||
| ETSY INC COM | COM | 29786A106 | 292 | 20,474 | SH | DFND | 4,980 | 0 | 15,494 | ||
| EVOLENT HEALTH INC CL A | COM | 30050B101 | 13,018 | 528,777 | SH | DFND | 77,048 | 0 | 451,729 | ||
| EXACT SCIENCES CORP | COM | 30063P105 | 72,429 | 3,900,300 | SH | DFND | 830,524 | 0 | 3,069,776 | ||
| FACEBOOK INC COM USD0.000006 CL A | COM | 30303M102 | 314,005 | 2,448,004 | SH | DFND | 620,263 | 0 | 1,827,741 | ||
| FAIRFAX INDIA HOLDINGS CORPORATION COM SUB VTG SHS ISIN #CA30389 | COM | 303897102 | 1,225 | 111,407 | SH | DFND | 33,140 | 0 | 78,267 | ||
| FARMER BROS CO COM | COM | 307675108 | 3,337 | 93,872 | SH | DFND | 21,645 | 0 | 72,227 | ||
| FB FINL CORP COM | COM | 30257X104 | 264 | 13,087 | SH | DFND | 3,422 | 0 | 9,665 | ||
| FEDERAL NATL MTG ASSN | COM | 313586109 | 50 | 29,651 | SH | DFND | 919 | 0 | 28,732 | ||
| FEVERTREE DRINKS PLC ORD GBP0.0025 ISIN #GB00BRJ9BJ26 SEDOL #BRJ | COM | G33929103 | 1,494 | 118,602 | SH | DFND | 74,199 | 0 | 44,403 | ||
| FIRST REP BK SAN FRANCISCO CAL COM | COM | 33616C100 | 35,501 | 460,388 | SH | DFND | 55,885 | 0 | 404,503 | ||
| FLEETCOR TECHNOLOGIES INC COM STK USD0.001 | COM | 339041105 | 13,905 | 80,040 | SH | DFND | 8,179 | 0 | 71,861 | ||
| FLEXION THERAPEUTICS INC COM | COM | 33938J106 | 77,888 | 3,986,098 | SH | DFND | 695,213 | 0 | 3,290,885 | ||
| FORTUNE BRANDS HOME & SECURITY INC USD0.01 | COM | 34964C106 | 69 | 1,180 | SH | DFND | 23 | 0 | 1,157 | ||
| FOUNDATION MEDICINE INC USD0.0001 | COM | 350465100 | 43,877 | 1,879,102 | SH | DFND | 496,406 | 0 | 1,382,696 | ||
| FRANCO NEVADA CORP COM ISIN #CA3518581051 SEDOL #B29NF31 | COM | 351858105 | 6,707 | 95,997 | SH | DFND | 2,715 | 0 | 93,282 | ||
| FULGENT GENETICS INC COM | COM | 359664109 | 77 | 8,334 | SH | DFND | 0 | 0 | 8,334 | ||
| GALAPAGOS NV NPV ISIN #BE0003818359 SEDOL #B07Q2V5 | COM | B44170106 | 22,818 | 355,400 | SH | DFND | 101,795 | 0 | 253,605 | ||
| GCP APPLIED TECHNOLOGIES INC COM | COM | 36164Y101 | 2,850 | 100,653 | SH | DFND | 26,218 | 0 | 74,435 | ||
| GENERAL FIN CORP DEL COM | COM | 369822101 | 27 | 6,000 | SH | DFND | 6,000 | 0 | 0 | ||
| GIGAMON INC COM USD0.0001 | COM | 37518B102 | 71,793 | 1,310,096 | SH | DFND | 139,432 | 0 | 1,170,664 | ||
| GILDAN ACTIVEWEAR INC COM ISIN #CA3759161035 SEDOL #2254645 | COM | 375916103 | 10,957 | 392,025 | SH | DFND | 38,399 | 0 | 353,626 | ||
| GILEAD SCIENCES INC | COM | 375558103 | 337 | 4,257 | SH | DFND | 817 | 0 | 3,440 | ||
| GLAUKOS CORP COM | COM | 377322102 | 60,844 | 1,612,194 | SH | DFND | 344,636 | 0 | 1,267,558 | ||
| GLOBANT SA USD1.20 | COM | L44385109 | 25,039 | 594,463 | SH | DFND | 201,068 | 0 | 393,395 | ||
| GMS INC COM | COM | 36251C103 | 1,505 | 67,699 | SH | DFND | 17,056 | 0 | 50,643 | ||
| GODADDY INC CL A | COM | 380237107 | 8,404 | 243,371 | SH | DFND | 40,332 | 0 | 203,039 | ||
| GOLD STD VENTURES CORP COM ISIN #CA3807381049 SEDOL #B05J9S2 | COM | 380738104 | 2,938 | 1,156,754 | SH | DFND | 104,900 | 0 | 1,051,854 | ||
| GOLDEN MINERALS CO COM ISIN #US3811191069 SEDOL #B3K4M51 | COM | 381119106 | 76 | 101,235 | SH | DFND | 9,362 | 0 | 91,873 | ||
| GOPRO INC CL A | COM | 38268T103 | 109 | 6,505 | SH | DFND | 594 | 0 | 5,911 | ||
| GRACE W R & CO DEL NEW | COM | 38388F108 | 16,982 | 230,106 | SH | DFND | 37,633 | 0 | 192,473 | ||
| GREEN BRICK PARTNERS INC | COM | 392709101 | 3,075 | 372,234 | SH | DFND | 4,082 | 0 | 368,152 | ||
| GRUPO FINANCIERO GALICIA SA ADR EACH REPR 10 CLASS B ARS1 LVL11 | COM | 399909100 | 81 | 2,608 | SH | DFND | 519 | 0 | 2,089 | ||
| GRUPO SUPERVIELLE S A SPONSORED ADR | COM | 40054A108 | 43,472 | 2,935,324 | SH | DFND | 582,401 | 0 | 2,352,923 | ||
| GTT COMMUNICATIONS INC COM USD0.0001 | COM | 362393100 | 46,997 | 1,997,318 | SH | DFND | 350,016 | 0 | 1,647,302 | ||
| GUIDEWIRE SOFTWARE INC COM USD0.0001 | COM | 40171V100 | 3,104 | 51,743 | SH | DFND | 10,372 | 0 | 41,371 | ||
| GYM GROUP PLC ORD GBP0.0001 144A ISIN #GB00BZBX0P70 SEDOL #BZBX0 | COM | G42114101 | 1,182 | 499,274 | SH | DFND | 128,931 | 0 | 370,343 | ||
| H &E EQUIPMENT SERVICES INC COM | COM | 404030108 | 2,373 | 141,613 | SH | DFND | 40,056 | 0 | 101,557 | ||
| HDFC BANK LTD ADS EACH REPR 3 INR10(MGT) | COM | 40415F101 | 71,619 | 996,233 | SH | DFND | 265,448 | 0 | 730,785 | ||
| HEALTHEQUITY INC COM | COM | 42226A107 | 5,540 | 146,368 | SH | DFND | 8,213 | 0 | 138,155 | ||
| HORIZON PHARMA PLC COM USD0.0001 | COM | G4617B105 | 4,569 | 252,031 | SH | DFND | 5,241 | 0 | 246,790 | ||
| HOTELES CITY EXPRESS SAB DE CV COM NPV ISIN #MX01HC000001 SEDOL | COM | P5184Q102 | 66 | 70,441 | SH | DFND | 13,836 | 0 | 56,605 | ||
| HUBSPOT INC COM | COM | 443573100 | 102,848 | 1,784,939 | SH | DFND | 284,085 | 0 | 1,500,854 | ||
| HYPOPORT FINANCE AG NPV (REGD) ISIN #DE0005493365 SEDOL #B28XLF6 | COM | ZZC39YMG4 | 75 | 798 | SH | DFND | 158 | 0 | 640 | ||
| ICICI BANK LIMITED ADR EACH REPR 2 ORD INR10(SPON) | COM | 45104G104 | 4,653 | 622,903 | SH | DFND | 22,615 | 0 | 600,288 | ||
| ILLUMINA INC COM | COM | 452327109 | 881 | 4,849 | SH | DFND | 1,012 | 0 | 3,837 | ||
| IMPINJ INC COM | COM | 453204109 | 54,684 | 1,461,362 | SH | DFND | 85,399 | 0 | 1,375,963 | ||
| INCYTE CORP COM | COM | 45337C102 | 58,979 | 625,503 | SH | DFND | 247,272 | 0 | 378,231 | ||
| INFINERA CORPORATION COM | COM | 45667G103 | 76 | 8,437 | SH | DFND | 1,024 | 0 | 7,413 | ||
| INPHI CORPORATION COM USD0.001 | COM | 45772F107 | 8,321 | 191,232 | SH | DFND | 31,973 | 0 | 159,259 | ||
| INSULET CORP COM | COM | 45784P101 | 40 | 982 | SH | DFND | 982 | 0 | 0 | ||
| INTL BUSINESS MACH | COM | 459200101 | 408 | 2,566 | SH | DFND | 1,061 | 0 | 1,505 | ||
| ITAU UNIBANCO HOLDINGS S.A. ADR EACH REPR 1 PRF NPV | COM | 465562106 | 3,356 | 306,808 | SH | DFND | 47,278 | 0 | 259,530 | ||
| JD COM INC SPONSORED ADR REPSTG COM CL A | COM | 47215P106 | 516 | 19,765 | SH | DFND | 3,172 | 0 | 16,593 | ||
| KANSAS CITY SOUTHERN COM | COM | 485170302 | 22,672 | 242,951 | SH | DFND | 22,365 | 0 | 220,586 | ||
| KORNIT DIGITAL LTD ORD ILS0.01 | COM | M6372Q113 | 5,871 | 625,887 | SH | DFND | 44,819 | 0 | 581,068 | ||
| KRAFT HEINZ CO COM | COM | 500754106 | 2,604 | 29,088 | SH | DFND | 5,697 | 0 | 23,391 | ||
| LGI HOMES INC COM | COM | 50187T106 | 78,966 | 2,143,479 | SH | DFND | 384,288 | 0 | 1,759,191 | ||
| LIBERTY MEDIA CORP DELAWARE COM A BRAVES GRP | COM | 531229706 | 3,850 | 220,637 | SH | DFND | 5,605 | 0 | 215,032 | ||
| LIBERTY MEDIA CORP DELAWARE COM C BRAVES GRP | COM | 531229888 | 4,689 | 269,796 | SH | DFND | 6,918 | 0 | 262,878 | ||
| LINKEDIN CORP COM USD0.0001 | COM | 53578A108 | 213 | 1,117 | SH | DFND | 621 | 0 | 496 | ||
| LIVEPERSON INC | COM | 538146101 | 4,197 | 499,053 | SH | DFND | 13,895 | 0 | 485,158 | ||
| LULULEMON ATHLETICA INC COM | COM | 550021109 | 3,210 | 52,648 | SH | DFND | 5,023 | 0 | 47,625 | ||
| LUMBER LIQUIDATORS HLDGS INC COM | COM | 55003T107 | 7,892 | 401,232 | SH | DFND | 74,294 | 0 | 326,938 | ||
| LUMENTUM HLDGS INC COM | COM | 55024U109 | 86,482 | 2,070,429 | SH | DFND | 298,017 | 0 | 1,772,412 | ||
| MALIBU BOATS INC COM CL A | COM | 56117J100 | 2,849 | 191,207 | SH | DFND | 20,829 | 0 | 170,378 | ||
| MARTIN MARIETTA MATLS INC | COM | 573284106 | 54,931 | 306,688 | SH | DFND | 30,430 | 0 | 276,258 | ||
| MASONITE INTERNATIONAL CORP COM NPV | COM | 575385109 | 52,336 | 841,819 | SH | DFND | 72,946 | 0 | 768,873 | ||
| MASTERCARD INCORPORATED CL A | COM | 57636Q104 | 11,594 | 113,927 | SH | DFND | 21,157 | 0 | 92,770 | ||
| MEETME INC COM USD0.001 | COM | 585141104 | 3,426 | 552,628 | SH | DFND | 104,986 | 0 | 447,642 | ||
| MEG ENERGY CORP COM ISIN #CA5527041084 SEDOL #B4XF9J1 | COM | 552704108 | 66 | 14,600 | SH | DFND | 3,600 | 0 | 11,000 | ||
| MERCADOLIBRE INC | COM | 58733R102 | 643 | 3,477 | SH | DFND | 853 | 0 | 2,624 | ||
| METRO BANK PLC ORD GBP0.000001 ISIN #GB00BZ6STL67 SEDOL #BZ6STL6 | COM | G60640102 | 76,068 | 2,120,938 | SH | DFND | 523,307 | 0 | 1,597,631 | ||
| MICROSOFT CORP | COM | 594918104 | 6,123 | 106,294 | SH | DFND | 16,418 | 0 | 89,876 | ||
| MINDBODY INC COM CL A | COM | 60255W105 | 5,126 | 260,714 | SH | DFND | 40,517 | 0 | 220,197 | ||
| MOBILEYE NV EUR0.01 | COM | N51488117 | 4,378 | 102,839 | SH | DFND | 9,271 | 0 | 93,568 | ||
| MORRISON(WM.)SUPERMA KETS ORD GBP0.10 ISIN #GB0006043169 SEDOL # | COM | G62748119 | 283 | 99,943 | SH | DFND | 23,334 | 0 | 76,609 | ||
| NANOSTRING TECHNOLOGIES INC COM USD0.0001 | COM | 63009R109 | 1,518 | 75,977 | SH | DFND | 18,366 | 0 | 57,611 | ||
| NATERA INC COM | COM | 632307104 | 355 | 31,933 | SH | DFND | 13,808 | 0 | 18,125 | ||
| NEOPHOTONICS CORP COM | COM | 64051T100 | 523 | 31,991 | SH | DFND | 3,398 | 0 | 28,593 | ||
| NETFLIX COM INC COM | COM | 64110L106 | 339,103 | 3,440,919 | SH | DFND | 785,080 | 0 | 2,655,839 | ||
| NETSUITE INC COM TENDER FROM CUSIP 64118Q107 | COM | 641998042 | 248 | 2,237 | SH | DFND | 272 | 0 | 1,965 | ||
| NEW HOME CO INC COM | COM | 645370107 | 346 | 32,441 | SH | DFND | 2,500 | 0 | 29,941 | ||
| NEW RELIC INC COM | COM | 64829B100 | 4,949 | 129,154 | SH | DFND | 21,650 | 0 | 107,504 | ||
| NIKE INC CLASS B | COM | 654106103 | 16 | 298 | SH | DFND | 0 | 0 | 298 | ||
| NINTENDO CO LTD ADR(8 CNV INTO 1 ORD)NPV | COM | 654445303 | 54,756 | 1,667,315 | SH | DFND | 334,079 | 0 | 1,333,236 | ||
| NINTENDO CO LTD NPV ISIN #JP3756600007 SEDOL #6639550 | COM | J51699106 | 761 | 2,895 | SH | DFND | 648 | 0 | 2,247 | ||
| NOBLE MIDSTREAM PARTNERS LP COM UNIT REPST | COM | 65506L105 | 275 | 9,847 | SH | DFND | 17 | 0 | 9,830 | ||
| NORTHERN DYNASTY MINS COM NPV ISIN #CA66510M2040 SEDOL #2637848 | COM | 66510M204 | 938 | 1,321,467 | SH | DFND | 52,042 | 0 | 1,269,425 | ||
| NUTANIX INC CL A | COM | 67059N108 | 11,100 | 300,000 | SH | DFND | 479 | 0 | 299,521 | ||
| NUVASIVE INC COM | COM | 670704105 | 2,039 | 30,581 | SH | DFND | 6,951 | 0 | 23,630 | ||
| NUVECTRA CORP COM | COM | 67075N108 | 5,604 | 809,770 | SH | DFND | 128,294 | 0 | 681,476 | ||
| NV5 GLOBAL INC COM | COM | 62945V109 | 6,089 | 188,449 | SH | DFND | 8,060 | 0 | 180,389 | ||
| NVIDIA CORP | COM | 67066G104 | 64 | 940 | SH | DFND | 214 | 0 | 726 | ||
| NXSTAGE MED INC COM | COM | 67072V103 | 147,209 | 5,890,709 | SH | DFND | 910,872 | 0 | 4,979,837 | ||
| OCADO GROUP PLC ORD GBP0.02 ISIN #GB00B3MBS747 SEDOL #B3MBS74 | COM | G6718L106 | 67,587 | 19,671,005 | SH | DFND | 3,430,326 | 0 | 16,240,679 | ||
| OCLARO INC COM NEW | COM | 67555N206 | 7,834 | 916,292 | SH | DFND | 158,545 | 0 | 757,747 | ||
| OPHTHOTECH CORP COM | COM | 683745103 | 65 | 1,411 | SH | DFND | 41 | 0 | 1,370 | ||
| ORBITAL ATK INC COM | COM | 68557N103 | 76 | 996 | SH | DFND | 204 | 0 | 792 | ||
| PACIFIC BIOSCIENCES CALIFORNIA INC COM USD0.0001 | COM | 69404D108 | 28,994 | 3,235,946 | SH | DFND | 1,013,047 | 0 | 2,222,899 | ||
| PACIFIC ETHANOL INC COM PAR $.001 | COM | 69423U305 | 15 | 2,218 | SH | DFND | 646 | 0 | 1,572 | ||
| PACIRA PHARMACEUTICALS INC COM USD0.001 | COM | 695127100 | 50,696 | 1,481,461 | SH | DFND | 509,395 | 0 | 972,066 | ||
| PALO ALTO NETWORKS INC COM USD0.0001 | COM | 697435105 | 8,469 | 53,152 | SH | DFND | 10,536 | 0 | 42,616 | ||
| PANDORA MEDIA INC COM | COM | 698354107 | 610 | 42,555 | SH | DFND | 14,975 | 0 | 27,580 | ||
| PARROT EUR0.1524 ISIN #FR0004038263 SEDOL #B04VST3 | COM | F7096P108 | 10,949 | 1,018,048 | SH | DFND | 265,090 | 0 | 752,958 | ||
| PAYCOM SOFTWARE INC COM USD0.01 | COM | 70432V102 | 116,807 | 2,330,087 | SH | DFND | 270,525 | 0 | 2,059,562 | ||
| PAYLOCITY HOLDING CORPORATION COM USD0.001 | COM | 70438V106 | 6,733 | 151,433 | SH | DFND | 26,362 | 0 | 125,071 | ||
| PDF SOLUTIONS INC | COM | 693282105 | 4,098 | 225,518 | SH | DFND | 36,305 | 0 | 189,213 | ||
| PENSKE AUTOMOTIVE GROUP INC | COM | 70959W103 | 4,008 | 83,182 | SH | DFND | 18,759 | 0 | 64,423 | ||
| PENUMBRA INC COM | COM | 70975L107 | 1,512 | 19,899 | SH | DFND | 3,750 | 0 | 16,149 | ||
| POOL CORP COM | COM | 73278L105 | 43,304 | 458,145 | SH | DFND | 62,349 | 0 | 395,796 | ||
| PRESTIGE BRANDS HLDGS INC | COM | 74112D101 | 948 | 19,648 | SH | DFND | 6,151 | 0 | 13,497 | ||
| PROOFPOINT INC COM USD0.0001 | COM | 743424103 | 10,153 | 135,645 | SH | DFND | 16,697 | 0 | 118,948 | ||
| PURE STORAGE INC CL A | COM | 74624M102 | 3,614 | 266,739 | SH | DFND | 31,212 | 0 | 235,527 | ||
| PURE TECHNOLOGIES LTD COM ISIN #CA7459151089 SEDOL #2797816 | COM | 745915108 | 5,301 | 1,188,839 | SH | DFND | 224,497 | 0 | 964,342 | ||
| PURPLEBRICKS GROUP PLC ORD GBP0.01 ISIN #GB00BYV2MV74 SEDOL #BYV | COM | G7S98A108 | 15,669 | 9,138,209 | SH | DFND | 2,770,398 | 0 | 6,367,811 | ||
| Q2 HLDGS INC COM | COM | 74736L109 | 44,069 | 1,537,661 | SH | DFND | 322,812 | 0 | 1,214,849 | ||
| REAL IND INC COM | COM | 75601W104 | 2,158 | 352,584 | SH | DFND | 107,140 | 0 | 245,444 | ||
| RED HAT INC COM | COM | 756577102 | 2,478 | 30,651 | SH | DFND | 6,843 | 0 | 23,808 | ||
| RENAISSANCERE HOLDINGS LTD COM STK USD1 | COM | G7496G103 | 20 | 167 | SH | DFND | 0 | 0 | 167 | ||
| RIGHTMOVE PLC WINTERHILL SHS ISIN #GB00B2987V85 SEDOL #B2987V8 | COM | G75657109 | 22,358 | 407,674 | SH | DFND | 56,219 | 0 | 351,455 | ||
| RINGCENTRAL INC-CLASS A | COM | 76680R206 | 88,412 | 3,736,792 | SH | DFND | 578,883 | 0 | 3,157,909 | ||
| SABRE CORP COM | COM | 78573M104 | 1,094 | 38,807 | SH | DFND | 9,651 | 0 | 29,156 | ||
| SAFETY INS GROUP INC | COM | 78648T100 | 2,189 | 32,565 | SH | DFND | 1,210 | 0 | 31,355 | ||
| SALESFORCE COM INC | COM | 79466L302 | 13,401 | 187,868 | SH | DFND | 37,611 | 0 | 150,257 | ||
| SAREPTA THERAPEUTICS INC COM | COM | 803607100 | 991 | 16,145 | SH | DFND | 6,288 | 0 | 9,857 | ||
| SCOUT24 AG NPV 144A ISIN #DE000A12DM80 SEDOL #BYT9340 | COM | D345XT105 | 72 | 2,177 | SH | DFND | 422 | 0 | 1,755 | ||
| SECTOR SPDR TR SHS BEN INT TECHNOLOGY | COM | 81369Y803 | 1,624 | 33,995 | SH | DFND | 8,206 | 0 | 25,789 | ||
| SERVICENOW INC COM USD0.001 | COM | 81762P102 | 8,330 | 105,240 | SH | DFND | 15,743 | 0 | 89,497 | ||
| SHAKE SHACK INC CL A | COM | 819047101 | 69,344 | 2,000,102 | SH | DFND | 475,828 | 0 | 1,524,274 | ||
| SHERWIN WILLIAMS CO | COM | 824348106 | 303 | 1,097 | SH | DFND | 30 | 0 | 1,067 | ||
| SHOPIFY INC NPV SUBORDINATED A ISIN #CA82509L1076 SEDOL #BX865C7 | COM | 82509L107 | 11,678 | 272,097 | SH | DFND | 50,378 | 0 | 221,719 | ||
| SIENTRA INC COM USD0.01 | COM | 82621J105 | 4,906 | 545,694 | SH | DFND | 57,690 | 0 | 488,004 | ||
| SIGNATURE BK NEW YORK N Y COM | COM | 82669G104 | 4,822 | 40,710 | SH | DFND | 6,909 | 0 | 33,801 | ||
| SILVER SPRING NETWORKS INC COM USD0.001 | COM | 82817Q103 | 5,942 | 419,053 | SH | DFND | 67,274 | 0 | 351,779 | ||
| SILVER WHEATON CORPORATION COM NPV ISIN #CA8283361076 SEDOL #B05 | COM | 828336107 | 2,719 | 100,580 | SH | DFND | 910 | 0 | 99,670 | ||
| SILVERCREST METALS INC COM NPV ISIN #CA8283631015 SEDOL #BYVY3D2 | COM | 828363101 | 1,592 | 846,919 | SH | DFND | 105,682 | 0 | 741,237 | ||
| SIRIUS XM HLDGS INC COM | COM | 82968B103 | 2,368 | 567,853 | SH | DFND | 79,803 | 0 | 488,050 | ||
| SITEONE LANDSCAPE SUPPLY INC COM | COM | 82982L103 | 12,333 | 343,251 | SH | DFND | 36,214 | 0 | 307,037 | ||
| SIX FLAGS ENTMT CORP NEW COM | COM | 83001A102 | 11,043 | 205,986 | SH | DFND | 64,280 | 0 | 141,706 | ||
| SPARK THERAPEUTICS INC COM | COM | 84652J103 | 690 | 11,495 | SH | DFND | 4,759 | 0 | 6,736 | ||
| SPIRIT AIRLS INC COM | COM | 848577102 | 31,515 | 741,015 | SH | DFND | 88,210 | 0 | 652,805 | ||
| SPLUNK INC COM USD0.001 | COM | 848637104 | 14,224 | 242,400 | SH | DFND | 46,223 | 0 | 196,177 | ||
| SPROUTS FMRS MKT INC COM | COM | 85208M102 | 151 | 7,312 | SH | DFND | 7,312 | 0 | 0 | ||
| SPS COMM INC COM | COM | 78463M107 | 2,077 | 28,290 | SH | DFND | 5,122 | 0 | 23,168 | ||
| SQUARE INC CL A | COM | 852234103 | 1,958 | 167,910 | SH | DFND | 46,768 | 0 | 121,142 | ||
| SS&C TECHNOLOGIES HLDGS INC COM | COM | 78467J100 | 23,809 | 740,554 | SH | DFND | 109,350 | 0 | 631,204 | ||
| STARBUCKS CORP COM USD0.001 | COM | 855244109 | 5,472 | 101,067 | SH | DFND | 19,336 | 0 | 81,731 | ||
| STRAIGHT PATH COMMUNICATIONS INC COM USD0.01 CL B | COM | 862578101 | 14,483 | 565,529 | SH | DFND | 110,499 | 0 | 455,030 | ||
| SUMMIT MATLS INC CL A | COM | 86614U100 | 5,552 | 299,300 | SH | DFND | 5,575 | 0 | 293,725 | ||
| SUNRUN INC COM | COM | 86771W105 | 429 | 68,146 | SH | DFND | 6,332 | 0 | 61,814 | ||
| SURGERY PARTNERS INC COM | COM | 86881A100 | 2,075 | 102,517 | SH | DFND | 486 | 0 | 102,031 | ||
| SVB FINL GROUP | COM | 78486Q101 | 2,010 | 18,185 | SH | DFND | 2,840 | 0 | 15,345 | ||
| T MOBILE US INC COM | COM | 872590104 | 229 | 4,904 | SH | DFND | 474 | 0 | 4,430 | ||
| TALEND SA ADR EACH REP 1 ORD SHS | COM | 874224207 | 1,164 | 44,481 | SH | DFND | 10,442 | 0 | 34,039 | ||
| TELADOC INC COM | COM | 87918A105 | 21 | 1,142 | SH | DFND | 193 | 0 | 949 | ||
| TENCENT HOLDINGS LIMITED HKD0.00002 ISIN #KYG875721634 SEDOL #BM | COM | G87572163 | 45,311 | 1,649,915 | SH | DFND | 409,304 | 0 | 1,240,611 | ||
| TESLA MOTORS INC COM USD0.001 | COM | 88160R101 | 157,145 | 770,204 | SH | DFND | 244,214 | 0 | 525,990 | ||
| THE TRADE DESK INC COM CL A | COM | 88339J105 | 446 | 15,274 | SH | DFND | 1 | 0 | 15,273 | ||
| THERAPEUTICSMD INC COM | COM | 88338N107 | 24,763 | 3,636,325 | SH | DFND | 1,167,997 | 0 | 2,468,328 | ||
| TIME INC NEW COM | COM | 887228104 | 30 | 2,056 | SH | DFND | 0 | 0 | 2,056 | ||
| TRACTOR SUPPLY CO | COM | 892356106 | 2,018 | 29,963 | SH | DFND | 7,688 | 0 | 22,275 | ||
| TRANSDIGM GROUP INC COM | COM | 893641100 | 15,765 | 54,527 | SH | DFND | 3,586 | 0 | 50,941 | ||
| TREVENA INC COM | COM | 89532E109 | 42 | 6,292 | SH | DFND | 4,176 | 0 | 2,116 | ||
| TRIPADVISOR INC COM | COM | 896945201 | 63,606 | 1,006,741 | SH | DFND | 237,975 | 0 | 768,766 | ||
| TSO3 INC COM ISIN #CA8730151013 SEDOL #2798518 | COM | 873015101 | 14,722 | 5,792,976 | SH | DFND | 551,277 | 0 | 5,241,699 | ||
| TWITTER INC COM USD0.000005 | COM | 90184L102 | 126 | 5,479 | SH | DFND | 5,479 | 0 | 0 | ||
| ULTA SALON COSMETCS &FRAG INC COM | COM | 90384S303 | 70,935 | 298,071 | SH | DFND | 40,043 | 0 | 258,028 | ||
| ULTIMATE SOFTWARE GROUP INC | COM | 90385D107 | 4,281 | 20,944 | SH | DFND | 3,806 | 0 | 17,138 | ||
| ULTRAGENYX PHARMACEUTICAL INC | COM | 90400D108 | 485 | 6,840 | SH | DFND | 2,747 | 0 | 4,093 | ||
| UNDER ARMOUR INC CL A | COM | 904311107 | 47,194 | 1,220,109 | SH | DFND | 290,643 | 0 | 929,466 | ||
| UNDER ARMOUR INC CL C | COM | 904311206 | 40,414 | 1,193,567 | SH | DFND | 285,777 | 0 | 907,790 | ||
| UNIVERSAL DISPLAY CORP | COM | 91347P105 | 187 | 3,361 | SH | DFND | 2,126 | 0 | 1,235 | ||
| VALIDUS HOLDING LTD COM STK USD0.175 | COM | G9319H102 | 5,490 | 110,193 | SH | DFND | 27,438 | 0 | 82,755 | ||
| VANECK VECTORS ETF TR GOLD MINERS ETF | COM | 92189F106 | 14,534 | 549,922 | SH | DFND | 17,308 | 0 | 532,614 | ||
| VEEVA SYS INC CL A COM | COM | 922475108 | 36,749 | 890,240 | SH | DFND | 229,245 | 0 | 660,995 | ||
| VULCAN MATERIALS CO | COM | 929160109 | 149 | 1,313 | SH | DFND | 43 | 0 | 1,270 | ||
| WALGREENS BOOTS ALLIANCE INC COM | COM | 931427108 | 340 | 4,221 | SH | DFND | 658 | 0 | 3,563 | ||
| WELLS FARGO & CO NEW | COM | 949746101 | 1,192 | 26,925 | SH | DFND | 4,372 | 0 | 22,553 | ||
| WORKDAY INC CL A | COM | 98138H101 | 7,359 | 80,260 | SH | DFND | 14,053 | 0 | 66,207 | ||
| XERO LIMITED NPV ISIN #NZXROE0001S2 SEDOL #B1Y43C7 | COM | Q98665104 | 21,766 | 1,546,854 | SH | DFND | 461,851 | 0 | 1,085,003 | ||
| XTERA COMMUNICATIONS INC COM | COM | 98415E300 | 14 | 25,004 | SH | DFND | 3,041 | 0 | 21,963 | ||
| XTREME DRILLING CORP ISIN #CA98419V1004 SEDOL #B7J8QB6 | COM | 98419V100 | 3,118 | 1,729,278 | SH | DFND | 160,207 | 0 | 1,569,071 | ||
| YOOX NET-A-PORTER GROUP NPV ISIN #IT0003540470 SEDOL #B4YC9W4 | COM | T9846S106 | 35,827 | 1,156,762 | SH | DFND | 78,080 | 0 | 1,078,682 | ||
| ZALANDO SE NPV ISIN #DE000ZAL1111 SEDOL #BQV0SV7 | COM | D98423102 | 645 | 15,647 | SH | DFND | 8,119 | 0 | 7,528 | ||
| ZAYO GROUP HLDGS INC COM | COM | 98919V105 | 44,938 | 1,512,568 | SH | DFND | 102,353 | 0 | 1,410,215 | ||
| ZELTIQ AESTHETICS INC COM | COM | 98933Q108 | 1,761 | 44,898 | SH | DFND | 13,899 | 0 | 30,999 | ||
| ZENDESK INC COM USD0.01 | COM | 98936J101 | 12,982 | 422,726 | SH | DFND | 82,838 | 0 | 339,888 | ||
| ZILLOW GROUP INC CL A | COM | 98954M101 | 18,835 | 546,727 | SH | DFND | 25,505 | 0 | 521,222 | ||
| ZILLOW GROUP INC CL C CAP STK | COM | 98954M200 | 39,745 | 1,147,028 | SH | DFND | 85,088 | 0 | 1,061,940 | ||
| ZOETIS INC COM USD0.01 CL A | COM | 98978V103 | 355 | 6,819 | SH | DFND | 237 | 0 | 6,582 | ||