EXHIBIT A

Agreement of Joint Filing

The undersigned hereby agree that a single Schedule 13G (or any amendment thereto) relating to the Common Stock of Monopar Therapeutics Inc. shall be filed on behalf of each of the undersigned and that this Agreement shall be filed as an exhibit to such Schedule 13G.

	AstraZeneca PLC
Dated: October 28, 2024	By:	/s/ Adrian Kemp
		Adrian Kemp
		Company Secretary

	Alexion Pharmaceuticals, Inc.
Dated: October 28, 2024	By:	/s/ Todd Spalding
		Todd Spalding
		Secretary

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