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Subsequent Events (Details) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended
Feb. 09, 2021
Feb. 01, 2021
Oct. 08, 2019
May 31, 2020
Sep. 30, 2021
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Subsequent events                
Undrawn committed bank facilities             $ 4,100  
Intangible assets           $ 20,947 $ 20,833 $ 21,959
Viela Bio                
Subsequent events                
Ownership     29.00% 26.70%        
Alexion Pharmaceuticals, Inc.                
Subsequent events                
Undrawn committed bank facilities           $ 17,500    
Sale of commercial rights | Crestor                
Subsequent events                
Consideration paid (received) $ (320)              
Intangible assets $ 0              
Major business combination | Alexion Pharmaceuticals, Inc. | Forecast                
Subsequent events                
Consideration paid (received)         $ 39,000      
Alexion shareholders ownership of combined company         15.00%      
Sale of ownership | Viela Bio                
Subsequent events                
Ownership   26.70%            
Sale of ownership | Viela Bio | Minimum                
Subsequent events                
Anticipated cash proceeds and profits   $ 760            
Sale of ownership | Viela Bio | Maximum                
Subsequent events                
Anticipated cash proceeds and profits   $ 780