X0303 4 2008-10-10 0000901219 HUMAN GENOME SCIENCES INC HGSI 0001262327 LAWLOR AUGUSTINE 55 CAMBRIDGE PARKWAY SUITE 301 CAMBRIDGE MA 02142 1 0 0 0 Common Stock 2008-10-10 4 A 0 2324 3.71 A 8542 D These shares were granted to the Reporting Person pursuant to the Non-Employee Director Equity Compensation Plan in a transaction exempt from Section 16(b) under Rule 16b-3. /s/Jeffrey Steinberg, Attorney-in-Fact for Augustine Lawlor 2008-10-14