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Proc-Type: 2001,MIC-CLEAR
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<SEC-DOCUMENT>0001225208-09-024643.txt : 20091217
<SEC-HEADER>0001225208-09-024643.hdr.sgml : 20091217
<ACCEPTANCE-DATETIME>20091217160944
ACCESSION NUMBER:		0001225208-09-024643
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20091215
FILED AS OF DATE:		20091217
DATE AS OF CHANGE:		20091217

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HUMAN GENOME SCIENCES INC
		CENTRAL INDEX KEY:			0000901219
		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
		IRS NUMBER:				223178468
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		14200 SHADY GROVE ROAD
		CITY:			ROCKVILLE
		STATE:			MD
		ZIP:			20850-3338
		BUSINESS PHONE:		3013098504

	MAIL ADDRESS:	
		STREET 1:		14200 SHADY GROVE ROAD
		CITY:			ROCKVILLE
		STATE:			MD
		ZIP:			20850

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Bateson Susan D.
		CENTRAL INDEX KEY:			0001191234

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-14169
		FILM NUMBER:		091247373

	MAIL ADDRESS:	
		STREET 1:		14200 SHADY GROVE ROAD
		CITY:			ROCKVILLE
		STATE:			MD
		ZIP:			20850

	FORMER NAME:	
		FORMER CONFORMED NAME:	MCKAY SUSAN D BATESON
		DATE OF NAME CHANGE:	20020920
</SEC-HEADER>
<DOCUMENT>
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<SEQUENCE>1
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            <rptOwnerZipCode>20850</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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            <officerTitle>Senior Vice President</officerTitle>
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    <footnotes>
        <footnote id="F1">8000 shares given to Mt Holyoke College; 900 shares given to the Universities at Shady Grove.</footnote>
        <footnote id="F2">These options are exercisable.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>Susan D. Bateson</signatureName>
        <signatureDate>2009-12-17</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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