POWER OF ATTORNEY


	KNOW ALL MEN BY THESE PRESENTS, that the person whose signature appears
below hereby constitutes and appoints James H. Davis, Barry A. Labinger or Alain
Cappeluti, his true and lawful attorney-in-fact, with full power of
substitution and resubstitution, to sign any and all instruments, certificates
and documents that may be necessary, desirable or appropriate to be executed
on behalf of himself, pursuant to Section 16 of the Securities and Exchange
Act of 1934, as amended (the "Exchange Act") and the regulations promulgated
there under, with respect to any and all filings relating to Human Genome
Sciences, Inc., and to file the same, with all exhibits thereto, and any other
documents in connection therewith, with the Securities and Exchange Commission,
and with any other entity when and if such is mandated by the Exchange Act, or
the Bylaws of the National Association of Securities Dealers, Inc., granting
unto said attorney-in-fact full power and authority to do and perform each and
every act and thing necessary, desirable or appropriate, fully to all intents
and purposes as he might or could do in person, thereby ratifying and
confirming all that said attorney-in-fact, or his substitutes, may lawfully do
or cause to be done by virtue hereof.   This Power of Attorney will remain in
effect for as long as the undersigned is subject to the reporting requirements
of Section 16 of the Exchange Act.

	IN WITNESS WHEREOF, this Power of Attorney has been signed as
of the 18th  day of January, 2006.

							/s/ Curran M. Simpson
							Curran M. Simpson

STATE OF MARYLAND 	)
				) ss.:
COUNTY OF MONTGOMERY  	)

	On this 18th day of January, 2006, before me personally appeared
Curran M. Simpson, to me known and known to me to be the individual
described herein, and who executed the foregoing certificate, and thereupon
duly acknowledged to me that he executed the same.


/s/ Rose Hadidian
Notary Public
My Commission Expires:  July 1, 2009