Investments - Additional Information (Detail) - USD ($)	3 Months Ended	9 Months Ended
	Sep. 30, 2022	Sep. 30, 2022	Dec. 31, 2021
Schedule Of Investments [Line Items]
Short-term investments	$ 110,738,000	$ 110,738,000	$ 79,932,000
Long-term investments	12,728,000	12,728,000	56,619,000
Interest on investments	700,000	1,600,000
Amortization on investments	200,000	600,000
Allowance for credit losses	0	0
Unrealized holding loss		1,200,000
Prepaid Expenses and Other Current Assets
Schedule Of Investments [Line Items]
Investment securities	600,000	600,000	300,000
Convertible Promissory Note | Thirona Bio, Inc.
Schedule Of Investments [Line Items]
Investment securities	$ 6,800,000	$ 6,800,000	$ 3,000,000.0