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Investments - Additional Information (Detail) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2022
Dec. 31, 2021
Schedule Of Investments [Line Items]      
Short-term investments $ 118,649,000 $ 118,649,000 $ 79,932,000
Long-term investments 32,596,000 32,596,000 56,619,000
Interest on investments 500,000 900,000  
Amortization on investments 200,000 500,000  
Allowance for credit losses 0 0  
Unrealized holding loss   1,200,000  
Prepaid Expenses and Other Current Assets      
Schedule Of Investments [Line Items]      
Investment securities 400,000 400,000 300,000
Convertible Promissory Note | Thirona Bio, Inc.      
Schedule Of Investments [Line Items]      
Investment securities $ 6,800,000 $ 6,800,000 $ 3,000,000.0