Accounts Receivable - Additional Information (Detail) $ in Millions	3 Months Ended
	Mar. 31, 2022 USD ($) Distributor
Accounts Receivable [Line Items]
Number of wholesale distributors | Distributor	3
Percentage of gross sales from major wholesale distributors	69.00%
Allowance for credit losses for accounts receivable	$ 0.8
Percentage of revenue from major customers collaborations and services	94.00%
United Therapeutics Corporation
Accounts Receivable [Line Items]
Percentage of collaborations and services net accounts receivables	100.00%
Vertice Pharma LLC
Accounts Receivable [Line Items]
Allowance for credit losses for accounts receivable	$ 0.8
Commercial product sales
Accounts Receivable [Line Items]
Percentage of accounts receivable from major wholesale distributors	74.00%