Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
CASH FLOWS FROM OPERATING ACTIVITIES:
Net loss	$ (80,926)	$ (57,240)
Adjustments to reconcile net loss to net cash used in operating activities:
Loss on extinguishment of debt, net	17,200	264
Stock-based compensation expense	12,200	6,511
Depreciation, amortization and accretion	4,215	2,149
Interest on milestone right	3,663
Write-off of inventory	1,902	496
Interest expense on promissory notes	1,598	5,148
Amortization of financing liability	1,372
Amortization of right-of-use assets	1,258	1,177
Asset impairment	106	1,889
(Gain) loss on foreign currency translation	(6,567)	8,006
In-process research and development		13,233
Other, net		19
Changes in operating assets and liabilities:
Accounts receivable, net	(776)	(705)
Inventory	(4,081)	(1,314)
Prepaid expenses and other current assets	(360)	(154)
Other assets	(138)	227
Accounts payable	1,374	793
Accrued expenses and other current liabilities	8,814	3,346
Deferred revenue	(14,567)	(5,910)
Recognized loss on purchase commitments	(5,892)	(4,751)
Operating lease liabilities	(2,135)	(1,312)
Accrued interest on Mann Group promissory notes	(4,919)
Deposits from customer	4,950
Net cash used in operating activities	(61,709)	(28,128)
CASH FLOWS FROM INVESTING ACTIVITIES:
Purchase of held-to-maturity debt securities	(196,131)
Proceeds from maturity of debt securities	59,060
Purchase of property and equipment	(11,466)	(801)
Purchase of available-for-sale securities	(3,000)
Proceeds from sale of treasury bills		20,000
Acquisition of in-process research and development, net of cash acquired		(3,983)
Net cash (used in) provided by investing activities	(151,537)	15,216
CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from the Senior convertible notes	230,000
Issuance costs associated with Senior convertible notes	(7,268)
Proceeds from the sale-leaseback transaction	102,250
Issuance costs associated with the sale-leaseback transaction	(3,120)
Deposit for the sale-leaseback transaction	(2,000)
Principal payments on Mann Group promissory notes	(35,051)
Payment of MidCap credit facility	(10,000)
Payment of MidCap credit facility prepayment penalty	(1,000)
Milestone payment	(5,000)
Payment of employment taxes related to vested restricted stock units and exercise of stock options	(498)	233
Proceeds from market price stock purchase plan	106	215
Issuance of common stock from the exercise of warrants		11,600
Proceeds from MidCap credit facility		10,000
Proceeds from PPP loan		4,873
Net cash provided by financing activities	270,267	49,853
NET INCREASE IN CASH AND CASH EQUIVALENTS AND RESTRICTED CASH	57,021	36,941
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, BEGINNING OF PERIOD	67,163	30,222
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, END OF PERIOD	124,184	67,163
At The Market Issuance
CASH FLOWS FROM FINANCING ACTIVITIES:
Issuance costs associated with the sale-leaseback transaction	(38)	(518)
Proceeds from public offering	$ 1,886	$ 23,450