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Collaboration, Licensing and Other Arrangements - Additional Information (Detail) - USD ($)
1 Months Ended 12 Months Ended 20 Months Ended
Oct. 16, 2021
Jul. 01, 2021
May 31, 2018
Dec. 31, 2021
Dec. 31, 2020
Nov. 30, 2020
Aug. 31, 2021
Aug. 12, 2021
Dec. 31, 2019
Oct. 31, 2018
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Total transaction price       $ 50,900,000            
Proceeds from related party       5,000,000.0            
Deferred revenue       20,370,000 $ 34,937,000       $ 40,847,000  
Deferred revenue - current       827,000 33,275,000          
Deferred revenue - non-current       19,543,000 1,662,000          
Revenue' collaborations and services       75,442,000 65,144,000          
Deferred revenue       20,370,000 34,937,000       $ 40,847,000  
Deferred revenue — current       827,000 33,275,000          
Deferred revenue — long term       19,543,000 1,662,000          
Collaborations and services                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Revenue' collaborations and services       36,274,000 32,820,000          
AFREZZA product sales                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Revenue' collaborations and services       39,168,000 32,324,000          
Collaboration and License Agreement | United Therapeutics Corporation                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Upfront payment received                   $ 45,000,000.0
Milestone Payment Received           $ 12,500,000        
Total transaction price       50,900,000            
Total anticipated cash flows [1] $ 463,500,000                  
Deferred revenue       18,600,000            
Deferred revenue - current       600,000            
Deferred revenue - non-current       18,000,000.0            
Deferred revenue       18,600,000            
Deferred revenue — current       600,000            
Deferred revenue — long term       18,000,000.0            
Collaboration and License Agreement | United Therapeutics Corporation | Clinical Supplies                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Total transaction price       105,800,000            
Collaboration and License Agreement | United Therapeutics Corporation | Maximum                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Additional option exercise and development milestone payments to be receive       40,000,000.0            
Collaboration and License Agreement | United Therapeutics Corporation | Manufacturing Services                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Allocated transaction price 144,500,000                  
Revenue recognized during period       $ 0            
Collaboration and License Agreement | United Therapeutics Corporation | Manufacturing Services | Transaction Price For The Contractual Obligations                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Total anticipated cash flows 64,300,000                  
Collaboration and License Agreement | United Therapeutics Corporation | Next-Gen R&D Services | Transaction Price For The Performance Obligations                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Total anticipated cash flows $ 399,200,000                  
Collaboration and License Agreement | Tyvaso DPI                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Total anticipated cash flows             $ 221,500,000 $ 221,500,000    
Commercial Supply Agreement                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Amendment description       As amended by an amendment dated October 16, 2021, the term of the CSA continues until December 31, 2031 (unless earlier terminated) and is thereafter renewed automatically for additional, successive two-year terms unless (i) United Therapeutics provides notice to the Company at least 24 months in advance of such renewal that United Therapeutics does not wish to renew the CSA or (ii) the Company provides notice to United Therapeutics at least 48 months in advance of such renewal that the Company does not wish to renew the CSA.            
Commercial Supply Agreement | United Therapeutics Corporation | Collaborations and services                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Revenue' collaborations and services       $ 267,000            
Co-Promotion Agreement                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Impairment on contract assets related to variable consideration       100,000            
Co-Promotion Agreement | Collaborations and services                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Reserve for allowance for doubtful accounts       800,000            
Co-Promotion Agreement | Vertice Pharma LLC                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Total transaction price       6,300,000            
Amendment to Co Promotion Agreement | Vertice Pharma LLC                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Percentage of modification of previously fixed consideration   50.00%                
Supply and Distribution Agreement | AFREZZA product sales | Biomm                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Revenue' collaborations and services       0 200,000          
License and Distribution Agreement | Cipla Ltd                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Deferred revenue       1,700,000            
Deferred revenue - current       100,000            
Deferred revenue - non-current       1,600,000            
Marketing and distribution agreement date     2018-05              
Deferred revenue       1,700,000            
Deferred revenue — current       100,000            
Deferred revenue — long term       1,600,000            
License and Distribution Agreement | Collaborations and services | Cipla Ltd                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Revenue' collaborations and services       $ 147,000 $ 147,000          
[1]

The total anticipated cash flow includes a transaction price of $64.3 million for the contractual obligations under the CSA for the Manufacturing Services and the Next-Gen R&D Services performance obligations and $399.2 million for future supply of Tyvaso DPI over the remaining term of the CSA.