Description of Business and Significant Accounting Policies (Tables)

3 Months Ended

Mar. 31, 2020

Schedule of Reconciliation of Cash, Cash Equivalents, and Restricted Cash

The following table provides a reconciliation of cash, cash equivalents, and restricted cash reported on the consolidated balance sheets that sum to amounts reported on the consolidated statement of cash flows (in thousands):

	March 31, 2020		December 31, 2019
Cash and cash equivalents	$	38,868	$	29,906
Restricted cash		316		316
Total cash, cash equivalents, and restricted cash	$	39,184	$	30,222

Schedule of Potentially Dilutive Common Stock Equivalent Securities

The computation of basic and diluted net loss per share for the three months ended March 31, 2020 and 2019 excludes the common stock equivalents of the following potentially dilutive securities because their inclusion would be anti-dilutive while the Company is in a net loss position:

	Three months ended March 31,
	2020		2019
Vesting of restricted stock units		522,021		1,314,218
Employee stock purchase plan		144,088		141,568
Exercise of common stock options		14,014,315		10,846,738
Conversion of 2024 convertible notes into common stock		1,666,667		3,629,627
Conversion of Mann Group convertible note into common stock		14,000,000		21,909,541
Exercise of common stock warrants		31,851		31,851
Exercise of warrants associated with Midcap Credit Facility		1,171,614		—
Exercise of warrants associated with public offering		7,250,000		26,666,667
Exercise of warrants associated with direct placement		—		14,000,000
Total shares		38,800,556		78,540,210