Commitments and Contingencies - Additional Information (Detail)						1 Months Ended		3 Months Ended	12 Months Ended
	Dec. 26, 2019 shares	Dec. 23, 2019 $ / shares shares	Aug. 02, 2019	Nov. 29, 2017 USD ($)	May 05, 2017 USD ($)	Jul. 31, 2019 shares	Dec. 31, 2018 $ / shares shares	Jun. 30, 2018 USD ($) Vehicle	Dec. 31, 2019 USD ($) Vehicle $ / shares shares	Dec. 31, 2018 USD ($) $ / shares shares	Aug. 06, 2019 $ / shares shares	Jan. 01, 2019 USD ($)	Jul. 01, 2013 USD ($)
Commitments And Contingencies [Line Items]
Purchase obligation extended term			2026
Supply Agreement expiration period									Dec. 31, 2026
Supply Agreement renewal period									2 years
Foreign currency hedging transactions period									90 days
Operating lease costs									$ 1,500,000
Operating lease, cash paid									1,800,000
Variable lease costs									$ 400,000
Operating lease, weighted average discount rate									7.50%
Operating lease, weighted-average remaining lease term									3 years
Underwriting Agreement with Leerink Partners LLC
Commitments And Contingencies [Line Items]
Exercise price of warrants | $ / shares		$ 1.311
Stock purchase agreements date							Dec. 31, 2018
Warrants modified | shares		11,750,000
Warrants exercised | shares		4,500,000
Warrants expired unexercised | shares	11,583,333
Warrants exercisable | shares									7,250,000
Underwriting Agreement with Leerink Partners LLC | Warrants
Commitments And Contingencies [Line Items]
Exercise price of warrants | $ / shares							$ 1.60		$ 1.60	$ 1.60
Repurchase of common stock , shares | shares						3,333,334
Lease Agreement with Enterprise | Vehicle Leases
Commitments And Contingencies [Line Items]
Number of vehicle leases | Vehicle								119	90
Operating lease rent expenses								$ 83,000	$ 65,000
Number of vehicle leases removed | Vehicle									29
Gain or loss recorded for leases removed									$ 0
Lease expiration period								48 months
Reduction in operating lease right-of-use assets									400,000
Reduction in operating lease liabilities									400,000
Operating lease right-of-use assets												$ 1,600,000
Operating lease liabilities									1,300,000			1,900,000
Operating lease, current assets									1,600,000
Operating lease, other current liabilities									600,000
Cost of Goods Sold
Commitments And Contingencies [Line Items]
Payment of long term purchase commitment, amendment fees									2,800,000	$ 2,000,000
Maximum | Underwriting Agreement with Leerink Partners LLC | Warrants
Commitments And Contingencies [Line Items]
Warrants to purchase common stock | shares							26,666,667			26,666,667
Minimum | Underwriting Agreement with Leerink Partners LLC
Commitments And Contingencies [Line Items]
Warrants exercised | shares		4,500,000
MidCap Credit Facility
Commitments And Contingencies [Line Items]
Exercise price of warrants | $ / shares											$ 1.11
Warrants to purchase of common stock | shares											1,171,614
Deerfield | Milestone Rights Liability
Commitments And Contingencies [Line Items]
Contingent liability remain payable									70,000,000
Deerfield | Milestone Rights Liability | Maximum
Commitments And Contingencies [Line Items]
Contingent liability for milestone payments													$ 90,000,000
Russell Ranch Road II LLC | Office Lease
Commitments And Contingencies [Line Items]
Operating lease rent expenses				$ 35,969	$ 40,951
Operating lease right-of-use assets												3,200,000
Operating lease liabilities									2,600,000			$ 3,500,000
Operating lease, other current liabilities									$ 900,000
Percentage of annual increase in lease payment				3.00%	3.00%
Lease expiration date				Jan. 31, 2023	Jan. 31, 2023
Lease renewal option				5 years	5 years
Reimbursement amount received for tenant improvements				$ 56,325
Operating lease rent expenses										$ 500,000