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Borrowings - Facility Financing Obligation - Additional Information (Detail) - USD ($)
3 Months Ended 12 Months Ended 24 Months Ended
Jul. 18, 2019
Dec. 31, 2019
Jun. 30, 2019
Dec. 31, 2014
Dec. 31, 2014
Dec. 31, 2018
Jul. 01, 2013
Debt Instrument [Line Items]              
Principal amount     $ 99,200,000        
Milestone rights liability     7,201,000     $ 7,201,000  
Deerfield | Milestone Rights Liability              
Debt Instrument [Line Items]              
Contingent liability for milestone payments     75,000,000        
Contingent liability for milestone payments, remain payable amount             $ 75,000,000
Deerfield | Milestone Rights Liability | Maximum              
Debt Instrument [Line Items]              
Contingent liability for milestone payments     90,000,000       90,000,000
Deerfield | Restricted Cash              
Debt Instrument [Line Items]              
Escrow deposit     5,000,000        
Deerfield | 2019 notes              
Debt Instrument [Line Items]              
Principal amount             $ 160,000,000
Debt instrument, remaining borrowing capacity     60,000,000        
Deerfield | 2019 notes | Subsequent Event              
Debt Instrument [Line Items]              
Repayments of debt $ 4,000,000            
Deerfield | Facility Financing Obligation              
Debt Instrument [Line Items]              
Principal amount     9,000,000        
Conversion of notes to common shares, value         $ 100,000,000    
Debt instrument, remaining borrowing capacity     80,000,000        
Debt issuance costs     200,000        
Remaining milestone rights liability     8,900,000     8,900,000  
Required payment for milestone liability     5,000,000        
Milestone rights liability     7,200,000     7,200,000  
Deerfield | Facility Financing Obligation | Scenario Forecast              
Debt Instrument [Line Items]              
Required payment for milestone liability   $ 5,000,000          
Deerfield | Facility Financing Obligation | Accrued Expenses and Other Current Liabilities              
Debt Instrument [Line Items]              
Milestone rights liability, current     1,600,000     $ 1,600,000  
Deerfield | Tranche B notes              
Debt Instrument [Line Items]              
Debt instument additional borrowing capacity       $ 20,000,000      
Debt instrument, remaining borrowing capacity     $ 20,000,000