Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Revenues:
Total revenues	$ 15,002	$ 3,893	$ 32,450	$ 7,358
Expenses:
Cost of goods sold	4,327	5,095	8,347	9,103
Research and development	1,632	2,967	3,299	5,611
Selling, general and administrative	16,609	21,731	42,282	42,349
(Gain) loss on foreign currency translation	1,247	(5,363)	(688)	(2,379)
Total expenses	25,954	24,430	56,916	54,684
Loss from operations	(10,952)	(20,537)	(24,466)	(47,326)
Other (expense) income:
Interest income	255	55	573	161
Interest expense on notes	(564)	(1,709)	(1,157)	(3,503)
Interest expense on note payable to related party	(1,109)	(1,046)	(2,189)	(2,160)
Gain (loss) on extinguishment of debt		772		(53)
Other income (expense)	(17)	30	(31)	61
Total other expense	(1,435)	(1,898)	(2,804)	(5,494)
Loss before provision for income taxes	(12,387)	(22,435)	(27,270)	(52,820)
Provision for income taxes		(240)		(240)
Net loss	$ (12,387)	$ (22,675)	$ (27,270)	$ (53,060)
Net loss per share - basic and diluted	$ (0.07)	$ (0.16)	$ (0.15)	$ (0.41)
Shares used to compute basic and diluted net loss per share	188,054	140,054	187,744	130,535
Commercial product sales
Revenues:
Total revenues	$ 6,065	$ 3,753	$ 11,141	$ 7,155
Collaborations and services
Revenues:
Total revenues	8,937	87	21,309	150
Expenses:
Cost of revenue	$ 2,139		$ 3,676
Revenue - other
Revenues:
Total revenues		$ 53		$ 53