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Collaboration and Licensing Arrangements (Tables)
 12 Months Ended
Dec. 31, 2018
Organization Consolidation And Presentation Of Financial Statements [Abstract]  
Schedule of Revenue from Collaboration and Services

Revenue from collaborations and services for the years ended December 31, 2018, 2017 and 2016 are as follows (in thousands):

 

 

 

December 31,

 

 

 

2018

 

 

2017

 

 

2016

 

United Therapeutics Agreement

 

$

6,386

 

 

$

—

 

 

$

—

 

United Therapeutics Research Agreement

 

 

3,758

 

 

 

—

 

 

 

—

 

Receptor Collaboration and License Agreement

 

 

341

 

 

 

250

 

 

 

—

 

Cipla Distribution Agreement

 

 

98

 

 

 

—

 

 

 

—

 

Sanofi License Agreement and Supply Agreement

 

 

—

 

 

 

—

 

 

 

171,965

 

 

 

$

10,583

 

 

$

250

 

 

$

171,965