Summary of Significant Accounting Policies (Tables) - Accounting Standards Update 2014-09

12 Months Ended

Dec. 31, 2018

Summary Of Significant Accounting Policies [Line Items]

Schedule of Cumulative Effect of Changes to Consolidated Balance Sheet for Adoption of New Revenue Guidance

The cumulative effect of the changes made to the consolidated January 1, 2018 balance sheet for the adoption of the new revenue guidance was as follows (in thousands):

	Balance at December 31, 2017			Adjustments due to new revenue guidance				Balance at January 1, 2018
Assets
Accounts receivable, net	$	2,789		$	(111	)	(1)	$	2,678
Deferred costs from commercial product    sales		405			(405	)	(2)		—
Liabilities
Accrued expenses and other current    liabilities	$	12,449		$	649		(3)	$	13,098
Deferred revenue, net		3,038			(3,038	)	(4)		—
Equity
Accumulated deficit	$	(2,854,898	)	$	1,873		(5)	$	(2,853,025	)

(1) To establish a reserve for product returns

(2) To eliminate deferred costs from commercial product sales previously required by the sell-through method

(3) To record additional accrual for estimated voucher payments related to inventory remaining in the distribution channel at January 1, 2018

(4) To eliminate deferred revenue previously required by the sell-through method

(5) To record the net impact of (1)-(4) in opening accumulated deficit

Schedule of Adoption of New Revenue Guidance Impact on Financial Statements

In accordance with the new revenue guidance, the disclosure of the impact of adoption on the consolidated balance sheet consolidated statement of operations and cash flows was as follows (in thousands):

Consolidated Balance Sheet
	For the year December 31, 2018
	As Reported			Adjustments			Balances without adoption of Topic 606
Assets
Accounts receivable, net	$	4,017		$	314		$	4,331
Deferred costs from commercial product    sales		—			875			875
Liabilities
Accrued expenses and other current    liabilities	$	15,022		$	(751	)	$	14,271
Deferred revenue, net		—			3,937			3,937
Equity
Accumulated deficit	$	(2,940,000	)	$	(1,997	)	$	(2,941,997	)
Consolidated Statement of    Operations
	For the year December 31, 2018
	As Reported			Adjustments			Balances without adoption of Topic 606
Revenue
Net revenue - commercial product sales	$	17,276		$	(486	)	$	16,790
Expenses
Cost of goods sold	$	19,402		$	(754	)	$	18,648
Net loss		(86,975	)		(267	)		(87,242	)
	For the year ended December 31, 2018
	As Reported			Adjustments			Balances without adoption of Topic 606
Cash Flows from Operating Activities
Net loss	$	(86,975	)	$	(267	)	$	(87,242	)
Change in:
Accounts receivable, net		(1,339	)		2,567			1,228
Deferred costs from commercial product    sales		—			470			470
Accrued expenses and other current    liabilities		2,249			(751	)		1,498
Deferred revenue, net		—			(899	)		(899	)
Cash (used in) provided by operating    activities		(37,731	)		1,120			(36,611	)