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Commitments and Contingencies - Additional Information (Detail)
$ / shares in Units, € in Millions
3 Months Ended 9 Months Ended 24 Months Ended
Apr. 05, 2018
USD ($)
$ / shares
shares
Apr. 02, 2018
EUR (€)
Nov. 29, 2017
USD ($)
Oct. 23, 2017
shares
May 05, 2017
USD ($)
Sep. 30, 2018
USD ($)
Jun. 30, 2018
USD ($)
Sep. 30, 2017
USD ($)
Sep. 30, 2018
USD ($)
Vehicle
Sep. 30, 2018
EUR (€)
Vehicle
Sep. 30, 2017
USD ($)
Oct. 01, 2018
USD ($)
Sep. 30, 2018
EUR (€)
Mar. 08, 2018
USD ($)
Dec. 31, 2017
USD ($)
Jul. 01, 2013
USD ($)
Commitments And Contingencies [Line Items]                                
Purchase commitment amount under Insulin Supply Agreement | €                   € 85.8            
Purchase obligation included in accounts payable                             $ 1,600,000  
Supply Agreement expiration period                 Dec. 31, 2023 Dec. 31, 2023            
Supply Agreement renewal period                 2 years 2 years            
Purchase requirement amount for remaining current year | €                         € 4.4      
Realized currency loss           $ (728,000)   $ 3,684,000 $ (3,107,000)   $ 12,077,000          
Amount of net proceeds from issuance of securities                 819,000              
Operating lease rent expenses           $ 100,000     $ 400,000              
Lease Agreement with Enterprise | Vehicle Leases                                
Commitments And Contingencies [Line Items]                                
Number of vehicle leases | Vehicle                 100 100            
Operating lease rent expenses                 $ 54,000              
Lease commencement period                 second quarter of 2018 second quarter of 2018            
Lease expiration period           48 months     48 months       48 months      
Common Stock                                
Commitments And Contingencies [Line Items]                                
Number of shares sold in underwritten public offering | shares       973,236                        
Purchase Agreements                                
Commitments And Contingencies [Line Items]                                
Stock purchase agreements date Apr. 05, 2018                              
Purchase Agreements | Common Stock                                
Commitments And Contingencies [Line Items]                                
Number of shares sold in underwritten public offering | shares 14,000,000                              
Amount of net proceeds from issuance of securities $ 26,400,000                              
Exchange price per share | $ / shares $ 2.00                              
Purchase Agreements | Warrants                                
Commitments And Contingencies [Line Items]                                
Warrants to purchase of common stock | shares 14,000,000                              
Exercise price of warrants | $ / shares $ 2.38                              
Supply Commitment                                
Commitments And Contingencies [Line Items]                                
Purchase commitment obligation           $ 100,000     $ 100,000              
Foreign Currency Hedging Transaction                                
Commitments And Contingencies [Line Items]                                
Purchase requirement amount for remaining current year | €   € 4.4                            
Foreign currency hedging transaction renewable period   90 days                            
Foreign Currency Hedging Transaction | Cost of Goods Sold                                
Commitments And Contingencies [Line Items]                                
Realized currency loss           100,000 $ 500,000                  
Scenario Forecast                                
Commitments And Contingencies [Line Items]                                
Purchase commitment cancellation fees                       $ 3,400,000        
Scenario Forecast | Before Amendment                                
Commitments And Contingencies [Line Items]                                
Purchase commitment cancellation fees                       $ 5,300,000        
Standby Letter of Credit | Vehicle Leases                                
Commitments And Contingencies [Line Items]                                
Maximum borrowing capacity                           $ 500,000    
Collateralized amount under letter of credit                           $ 500,000    
Amount drawn down on letter of credit           0     0              
Deerfield | Milestone Rights Liability                                
Commitments And Contingencies [Line Items]                                
Contingent liability for milestone payments, remain payable amount           75,000,000     75,000,000             $ 75,000,000
Deerfield | Milestone Rights Liability | Maximum                                
Commitments And Contingencies [Line Items]                                
Contingent liability for milestone payments           $ 90,000,000     $ 90,000,000             $ 90,000,000
Russell Ranch Road II LLC                                
Commitments And Contingencies [Line Items]                                
Operating lease rent expenses     $ 35,969   $ 40,951                      
Percentage of annual increase in lease payment     3.00%   3.00%                      
Lease expiration date     Jan. 31, 2023   Jan. 31, 2023                      
Lease renewal option     5 years   5 years                      
Maximum reimbursable amount for tenant improvements     $ 56,325