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Fair Value of Financial Instruments (Detail) - USD ($)
$ in Millions
Sep. 30, 2018
Dec. 31, 2017
Financial liabilities:    
Financial liabilities fair value $ 130.8 $ 93.5
Milestone Rights Liability    
Financial liabilities:    
Financial liabilities fair value 19.0 19.1
Carrying Value    
Financial liabilities:    
Financial liabilities fair value 114.2 85.9
Carrying Value | Milestone Rights Liability    
Financial liabilities:    
Financial liabilities fair value 8.8 8.8
Estimate of Fair Value Measurement | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value 130.8 93.5
Estimate of Fair Value Measurement | Milestone Rights Liability | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value 19.0 19.1
5.75% Senior convertible notes due October 23, 2021    
Financial liabilities:    
Financial liabilities fair value 19.7 19.8
5.75% Senior convertible notes due October 23, 2021 | Carrying Value    
Financial liabilities:    
Financial liabilities fair value 19.1 24.4
5.75% Senior convertible notes due October 23, 2021 | Estimate of Fair Value Measurement | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value 19.7 19.8
Facility Financing Obligation    
Financial liabilities:    
Financial liabilities fair value 11.4 54.6
Facility Financing Obligation | Carrying Value    
Financial liabilities:    
Financial liabilities fair value 14.2 52.7
Facility Financing Obligation | Estimate of Fair Value Measurement | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value 11.4 $ 54.6
Note Payable to Related Party    
Financial liabilities:    
Financial liabilities fair value 80.7  
Note Payable to Related Party | Carrying Value    
Financial liabilities:    
Financial liabilities fair value 72.1  
Note Payable to Related Party | Estimate of Fair Value Measurement | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value $ 80.7