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Borrowings - Facility Financing Obligation (2019 Notes and Tranche B Notes) - Additional Information (Detail)
1 Months Ended 3 Months Ended 9 Months Ended
Oct. 18, 2018
USD ($)
Sep. 26, 2018
USD ($)
Sep. 05, 2018
USD ($)
shares
Jul. 12, 2018
USD ($)
$ / shares
shares
Jun. 08, 2018
USD ($)
$ / shares
shares
Mar. 12, 2018
USD ($)
shares
Mar. 06, 2018
USD ($)
d
$ / shares
shares
Jan. 18, 2018
USD ($)
d
$ / shares
shares
Jan. 15, 2018
USD ($)
Nov. 06, 2017
USD ($)
$ / shares
shares
Oct. 23, 2017
USD ($)
d
$ / shares
shares
Jun. 29, 2017
USD ($)
$ / shares
shares
Apr. 18, 2017
USD ($)
$ / shares
shares
Sep. 30, 2018
USD ($)
shares
Aug. 31, 2018
USD ($)
Sep. 30, 2018
USD ($)
shares
Sep. 30, 2018
USD ($)
shares
Sep. 30, 2017
USD ($)
Dec. 31, 2018
USD ($)
Oct. 31, 2018
USD ($)
Oct. 16, 2018
USD ($)
Sep. 07, 2018
$ / shares
Sep. 06, 2018
$ / shares
Jun. 07, 2018
USD ($)
$ / shares
Mar. 09, 2018
$ / shares
Dec. 31, 2017
USD ($)
shares
Jul. 01, 2013
USD ($)
Debt Instrument [Line Items]                                                      
Principal amount                           $ 104,700,000   $ 104,700,000 $ 104,700,000                    
Loss on extinguishment of debt                               712,000 765,000 $ 830,000                  
Cash and cash equivalents                           $ 10,446,000   $ 10,446,000 $ 10,446,000                 $ 43,946,000  
Common stock, shares issued | shares                           159,497,573   159,497,573 159,497,573                 119,053,414  
Milestone rights liability, noncurrent                           $ 7,202,000   $ 7,202,000 $ 7,202,000                 $ 7,201,000  
Common Stock                                                      
Debt Instrument [Line Items]                                                      
Number of shares sold in underwritten public offering | shares                     973,236                                
Senior convertible notes due December 31, 2019                                                      
Debt Instrument [Line Items]                                                      
Principal amount                           12,000,000   12,000,000 12,000,000                    
Conversion of notes to common shares, value             $ 1,300,000                                        
Exchange price per share | $ / shares             $ 2.83         $ 1.45 $ 1.22                            
Loss on extinguishment of debt                       $ 500,000                              
Cash repayment                         $ 4,000,000                            
Debt extinguishment amount                       5,000,000                              
Debt discount and issuance costs                       300,000                              
Number of trading days | d             3                                        
Senior convertible notes due December 31, 2019 | Common Stock                                                      
Debt Instrument [Line Items]                                                      
Conversion Option, shares | shares             441,618                                        
Senior convertible notes due December 31, 2019 | Tranche B Notes                                                      
Debt Instrument [Line Items]                                                      
Principal amount                           14,495,000   14,495,000 14,495,000                 54,407,000  
Loss on extinguishment of debt                         300,000                            
2019 Notes and Tranche B Notes | Fourth Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Deferred payment of credit facility principal amount                     $ 10,000,000                                
Deerfield | Ninth Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Exchange price per share | $ / shares                                           $ 1.78 $ 2.04        
Loss on extinguishment of debt                               700,000 $ 700,000                    
Debt discount and issuance costs     $ 300,000                                                
Deerfield | Tenth Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Debt instrument, payment terms description                                 further defer the payment of $3.0 million in principal amount of 2019 notes from September 30, 2018 until the earlier of October 31, 2018 or the first business day following the date the Company receives an upfront payment of $45.0 million from United Therapeutics                    
Available amount of credit facility under covenant restrictions for each quarter end after current fiscal   $ 25,000,000                                                  
Deerfield | Tenth Amendment to Facility Agreement | Subsequent Event | United Therapeutics Corporation                                                      
Debt Instrument [Line Items]                                                      
Upfront payment received                                         $ 45,000,000            
Deerfield | Minimum | Tenth Amendment to Facility Agreement | Scenario Forecast                                                      
Debt Instrument [Line Items]                                                      
Available amount of credit facility under covenant restrictions                                     $ 20,000,000                
Deerfield | Minimum | Tenth Amendment to Facility Agreement | Subsequent Event                                                      
Debt Instrument [Line Items]                                                      
Available amount of credit facility under covenant restrictions                                       $ 20,000,000              
Deerfield | Tranche B Notes                                                      
Debt Instrument [Line Items]                                                      
Principal amount                           20,000,000   20,000,000 $ 20,000,000                    
Deerfield | Tranche B Notes | Facility Agreement Eighth Amendment | Notes Due and Payable on December 31, 2019                                                      
Debt Instrument [Line Items]                                                      
Principal amount       $ 2,000,000                                              
Conversion of notes to common shares, value       $ 2,000,000                                              
Deerfield | Tranche B Notes | Ninth Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Conversion of notes to common shares, value     2,500,000                                                
Deerfield | Tranche B Exchange Shares                                                      
Debt Instrument [Line Items]                                                      
Conversion of notes to common shares, value           $ 5,000,000                                          
Conversion Option, shares | shares           1,838,236                                          
Exchange price per share | $ / shares                                                 $ 2.72    
Deerfield | Milestone Rights Liability                                                      
Debt Instrument [Line Items]                                                      
Contingent liability for milestone payments, remain payable amount                           75,000,000   75,000,000 75,000,000                   $ 75,000,000
Deerfield | Milestone Rights Liability | Maximum                                                      
Debt Instrument [Line Items]                                                      
Contingent liability for milestone payments                           90,000,000   90,000,000 90,000,000                   $ 90,000,000
Deerfield | Senior convertible notes due December 31, 2019                                                      
Debt Instrument [Line Items]                                                      
Principal amount                           120,000,000   120,000,000 120,000,000                    
Milestone rights liability, noncurrent                           7,200,000   7,200,000 7,200,000                 7,200,000  
Remaining milestone rights liability                           8,800,000   8,800,000 8,800,000                 8,800,000  
Deerfield | Senior convertible notes due December 31, 2019 | Accrued Expenses and Other Current Liabilities                                                      
Debt Instrument [Line Items]                                                      
Milestone rights liability, current                           1,600,000   1,600,000 1,600,000                 $ 1,600,000  
Deerfield | Senior convertible notes due December 31, 2019 | Fifth Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Deferred payment of credit facility principal amount                 $ 4,400,000                                    
Deerfield | Senior convertible notes due December 31, 2019 | Sixth Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Conversion of notes to common shares, value               $ 3,200,000                                      
Exchange price per share | $ / shares               $ 2.49                                      
Deferred payment of credit facility principal amount               $ 1,300,000                                      
Common stock, shares issued | shares               1,267,972                                      
Deerfield | Senior convertible notes due December 31, 2019 | Seventh Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Conversion Option, shares | shares         3,061,224                                            
Exchange price per share | $ / shares         $ 1.96                                            
Cash and cash equivalents         $ 20,000,000                                            
Deerfield | Senior convertible notes due December 31, 2019 | Seventh Amendment to Facility Agreement | 2019 Notes Due And Payable On July 1, 2018                                                      
Debt Instrument [Line Items]                                                      
Principal amount         5,000,000                                            
Conversion of notes to common shares, value         $ 3,000,000                                            
Deerfield | Senior convertible notes due December 31, 2019 | Facility Agreement Third Amendment                                                      
Debt Instrument [Line Items]                                                      
Cash repayment of senior notes under exchange agreement                       10,000,000                              
Conversion of notes to common shares, value                       $ 5,000,000                              
Conversion Option, shares | shares                       3,584,230                              
Exchange price per share | $ / shares                       $ 1.395                              
Cash and cash equivalents                       $ 10,000,000                              
Deerfield | Senior convertible notes due December 31, 2019 | Facility Agreement Eighth Amendment                                                      
Debt Instrument [Line Items]                                                      
Cash repayment of senior notes under exchange agreement                             $ 3,000,000                        
Common stock, shares issued | shares       7,367,839                                              
Deerfield | Senior convertible notes due December 31, 2019 | Facility Agreement Eighth Amendment | Notes Due and Payable on July 18, 2018                                                      
Debt Instrument [Line Items]                                                      
Principal amount       $ 10,000,000                                              
Conversion of notes to common shares, value       7,000,000                                              
Deerfield | Senior convertible notes due December 31, 2019 | Facility Agreement Eighth Amendment | Notes Due and Payable on December 31, 2019                                                      
Debt Instrument [Line Items]                                                      
Principal amount       5,000,000                                              
Conversion of notes to common shares, value       $ 3,000,000                                              
Deerfield | Senior convertible notes due December 31, 2019 | Ninth Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Cash repayment of senior notes under exchange agreement                           3,000,000                          
Conversion of notes to common shares, value     $ 8,000,000                                                
Deerfield | Senior convertible notes due December 31, 2019 | Tenth Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Cash repayment of senior notes under exchange agreement   $ 3,000,000                                                  
Deerfield | Senior convertible notes due December 31, 2019 | Tenth Amendment to Facility Agreement | Subsequent Event                                                      
Debt Instrument [Line Items]                                                      
Cash repayment of senior notes under exchange agreement $ 3,000,000                                                    
Deerfield | Senior convertible notes due December 31, 2019 | Minimum | Seventh Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Cash and cash equivalents                                               $ 25,000,000      
Deerfield | Senior convertible notes due December 31, 2019 | Minimum | Facility Agreement Third Amendment                                                      
Debt Instrument [Line Items]                                                      
Cash and cash equivalents                       $ 25,000,000           $ 10,000,000                  
Deerfield | Senior convertible notes due December 31, 2019 | Minimum | Facility Agreement Eighth Amendment | Common Stock                                                      
Debt Instrument [Line Items]                                                      
Conversion price of shares | $ / shares       $ 1.80                                              
Deerfield | Senior convertible notes due December 31, 2019 | Maximum | Facility Agreement Eighth Amendment | Common Stock                                                      
Debt Instrument [Line Items]                                                      
Conversion Option, shares | shares       5,750,000                                              
Conversion price of shares | $ / shares       $ 2.01                                              
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Notes                                                      
Debt Instrument [Line Items]                                                      
Cash repayment of senior notes under exchange agreement                         4,000,000                            
Conversion of notes to common shares, value                         $ 1,000,000                            
Available amount of credit facility under covenant restrictions for each quarter end after current fiscal                           $ 25,000,000   $ 25,000,000 $ 25,000,000                    
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Notes | Minimum | Scenario Forecast                                                      
Debt Instrument [Line Items]                                                      
Available amount of credit facility under covenant restrictions                                     $ 20,000,000                
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Notes | Minimum | Subsequent Event                                                      
Debt Instrument [Line Items]                                                      
Available amount of credit facility under covenant restrictions                                       $ 20,000,000              
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Exchange Shares                                                      
Debt Instrument [Line Items]                                                      
Conversion Option, shares | shares                         869,565                            
Exchange price per share | $ / shares                         $ 1.15                            
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Exchange Shares | Fourth Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Conversion of notes to common shares, value                   $ 5,600,000                                  
Conversion Option, shares | shares                   1,720,846                                  
Conversion price of shares | $ / shares                   $ 3.25                                  
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Exchange Shares | Sixth Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Number of trading days | d               3                                      
Conversion price of shares | $ / shares               $ 2.75                                      
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Exchange Shares | Seventh Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Conversion price of shares | $ / shares         $ 2.01                                     $ 2.75      
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Exchange Shares | Seventh Amendment to Facility Agreement | Tranche B Notes Due and Payable on December 31, 2019                                                      
Debt Instrument [Line Items]                                                      
Principal amount         $ 5,000,000                                            
Conversion of notes to common shares, value         $ 3,000,000                                            
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Exchange Shares | Common Stock | Sixth Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Number of shares sold in underwritten public offering | shares               10,000,000                                      
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Exchange Shares | Maximum | Seventh Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Conversion Option, shares | shares         9,558,382                                            
Deerfield | Senior convertible notes due December 31, 2019 | Tranche 1 Notes                                                      
Debt Instrument [Line Items]                                                      
Conversion of notes to common shares, value                         $ 5,000,000                            
Conversion Option, shares | shares                         4,347,826                            
Deerfield | 2019 Notes and Tranche B Notes | Ninth Amendment to Facility Agreement | Common Stock                                                      
Debt Instrument [Line Items]                                                      
Conversion Option, shares | shares     5,749,500                                                
Deerfield | 2019 Notes and Tranche B Notes | Tranche B Exchange Shares | Fourth Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Number of trading days | d                     3                                
Conversion price of shares | $ / shares                     $ 3.25                                
Deerfield | 2019 Notes and Tranche B Notes | Tranche B Exchange Shares | Maximum | Common Stock | Fourth Amendment to Facility Agreement                                                      
Debt Instrument [Line Items]                                                      
Number of shares sold in underwritten public offering | shares                     4,000,000