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Description of Business and Significant Accounting Policies - Additional Information (Detail)
3 Months Ended 9 Months Ended 12 Months Ended
Mar. 01, 2017
Sep. 30, 2018
USD ($)
Distributor
Sep. 30, 2017
USD ($)
Sep. 30, 2018
USD ($)
Distributor
Contract
Sep. 30, 2017
USD ($)
Dec. 31, 2017
USD ($)
Distributor
Contract
Dec. 31, 2018
USD ($)
Oct. 31, 2018
USD ($)
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]                
Accumulated deficit   $ (2,930,249,000)   $ (2,930,249,000)   $ (2,854,898,000)    
Reclassification from changes in inventory to inventory write-off   1,000,000   1,792,000 $ 1,793,000      
Reclassification from other to loss on sale, abandonment/disposal or impairment of property and equipment       (10,000) $ 179,000      
Cash and cash equivalents   10,446,000   10,446,000   43,946,000    
Restricted cash   527,000   527,000   4,409,000    
Principal amount of outstanding borrowings   $ 104,700,000   $ 104,700,000        
Stock split of common stock 0.2              
Reverse stock split, description       The Company’s board of directors approved a 1-for-5 reverse stock split of the Company’s outstanding common stock. On March 1, 2017, the Company filed with the Secretary of State of the State of Delaware a Certificate of Amendment of the Company’s Amended and Restated Certificate of Incorporation (the “Charter Amendment”) to effect the 1-for-5 reverse stock split of the Company’s outstanding common stock (the “Reverse Stock Split”) . The Company’s common stock began trading on the Nasdaq Global Market on a split-adjusted basis when the market opened on March 3, 2017. As a result, prior to March 3, 2017, all common stock share amounts included in these condensed consolidated financial statements have been retroactively reduced by a factor of five, and all common stock per share amounts have been increased by a factor of five, with the exception of the Company’s common stock par value.        
Net deferred revenue           $ 3,038,000    
Number of wholesale distributors | Distributor   3   3   3    
Percentage of product shipments to wholesale distributors   90.00% 92.00% 89.00% 92.00%      
Revenue - other   $ 4,469,000 $ 2,043,000 $ 11,827,000 $ 7,215,000      
Loss on purchase commitments       $ 100,400,000        
Loss on purchase commitments, number of new contracts recognized | Contract       0   0    
Accounting Standards Update 2016-02                
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]                
Increase of assets and liabilities arising from operating leases upon adoption of ASU   $ 6,000,000   $ 6,000,000        
Third party logistics                
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]                
Net deferred revenue           $ 1,500,000    
AFREZZA product sales                
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]                
Estimated current return reserve rate   3.80%   3.80%        
Revenue - other   $ 4,387,000 $ 1,981,000 $ 11,542,000 4,726,000      
Bulk insulin sales and sale of intellectual property                
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]                
Revenue - other         $ 2,300,000      
Senior convertible notes due December 31, 2019                
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]                
Senior notes, effective interest rate   9.75%   9.75%        
Principal amount of outstanding borrowings   $ 12,000,000   $ 12,000,000        
Senior convertible notes due December 31, 2019 | Tranche B Notes                
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]                
Principal amount of outstanding borrowings   14,495,000   14,495,000   $ 54,407,000    
Deerfield | Tranche B Notes                
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]                
Principal amount of outstanding borrowings   $ 20,000,000   $ 20,000,000        
Deerfield | Senior convertible notes due December 31, 2019                
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]                
Senior notes, effective interest rate   9.75%   9.75%        
Principal amount of outstanding borrowings   $ 120,000,000   $ 120,000,000        
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Notes                
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]                
Available amount of credit facility under covenant restrictions for each quarter end after current fiscal   $ 25,000,000   $ 25,000,000        
Senior notes, effective interest rate   8.75%   8.75%        
Minimum | AFREZZA product sales                
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]                
Sales return right following product expiration in months       6 months        
Minimum | Deerfield | Senior convertible notes due December 31, 2019 | Subsequent Event | Tranche B Notes                
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]                
Available amount of credit facility under covenant restrictions               $ 20,000,000
Minimum | Deerfield | Scenario Forecast | Senior convertible notes due December 31, 2019 | Tranche B Notes                
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]                
Available amount of credit facility under covenant restrictions             $ 20,000,000  
Maximum | AFREZZA product sales                
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]                
Sales return right following product expiration in months       12 months