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Subsequent Events - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended
May 08, 2018
Apr. 05, 2018
Oct. 23, 2017
Mar. 31, 2018
Subsequent Event [Line Items]        
Amount of net proceeds from issuance of securities       $ 634
Common Stock        
Subsequent Event [Line Items]        
Number of shares sold in underwritten public offering     973,236  
Subsequent Event | Cipla Ltd        
Subsequent Event [Line Items]        
Marketing and distribution agreement date May 08, 2018      
Upfront payment received $ 2,200      
Subsequent Event | Purchase Agreements        
Subsequent Event [Line Items]        
Stock purchase agreements date   Apr. 05, 2018    
Subsequent Event | Purchase Agreements | Common Stock        
Subsequent Event [Line Items]        
Number of shares sold in underwritten public offering   14,000,000    
Amount of net proceeds from issuance of securities   $ 26,300    
Exchange price per share   $ 2.00    
Subsequent Event | Purchase Agreements | Warrants        
Subsequent Event [Line Items]        
Warrants to purchase of common stock   14,000,000    
Exercise price of warrants   $ 2.38