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Stock Award Plans - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
Mar. 31, 2014
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
May 23, 2013
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Shares reserved under ESPP 10.00%        
Shares sold to employees   199,578 104,758 64,245  
Shares purchased under ESPP   136,660      
Options to purchase common stock   7,089,440 5,530,256    
Stock-based compensation   $ 4,847 $ 5,135 $ 8,725  
Weighted average grant date fair value of the stock options granted   $ 1.19 $ 3.05 $ 12.80  
Total intrinsic value of options exercised     $ 100 $ 6,200  
Cash received from the exercise of options   $ 20 500 3,300  
Weighted-average remaining contractual term, options outstanding   6 years 10 months 13 days      
Weighted-average remaining contractual term, options vested and expected to vest   6 years 9 months      
Weighted-average remaining contractual term, options excerisable   3 years 6 months 25 days      
Restricted stock units expected to vest   939,240      
Weighted average grant date fair value   $ 4.28      
Total intrinsic value of restricted stock units expected to vest   $ 2,200      
Total intrinsic value of restricted stock units vested   400 600 5,200  
Fair value of restricted stock units vested   $ 1,900 2,600 5,500  
Weighted average vesting period for unrecognized compensation expense   2 years 3 months 18 days      
Stock compensation expense   $ 4,847 5,135 8,725  
Consultant          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Options to purchase common stock   23,047      
Stock-based compensation       318  
Executive Officer | Employee Severance          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock compensation expense       $ 1,600  
Stock Options          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Vesting period   36 months      
Vesting rights percentage   25.00%      
Unrecognized compensation expense related to options   $ 2,900      
Restricted Stock          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Vesting period   4 years      
Restricted Stock | Tranche One          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Vesting rights percentage   25.00%      
Restricted Stock Units          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Unrecognized compensation expense related to non-option   $ 3,200      
Performance-based Stock Options          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Unrecognized compensation expense related to options   3,500      
Compensation cost   $ 900 $ 300    
Minimum          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Share of common stock outstanding 1.00%        
Vesting period   4 years      
Maximum          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Vesting period   10 years      
2013 Equity Incentive Plan          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Equity incentive plan, shares         4,300,000
Options to purchase common stock   5,795,035      
Employee Stock Purchase Plans          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Shares reserved for issuance 400,000 246,205      
Share reserve automatic increase each year 140,000