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Commitments and Contingencies - Additional Information (Detail)
$ / shares in Units, € in Millions
1 Months Ended 9 Months Ended 24 Months Ended
Oct. 23, 2017
shares
Sep. 29, 2017
USD ($)
shares
May 05, 2017
USD ($)
May 31, 2016
USD ($)
$ / shares
shares
Sep. 30, 2017
USD ($)
Sep. 30, 2017
EUR (€)
Oct. 01, 2018
USD ($)
Oct. 03, 2017
shares
Jul. 01, 2013
USD ($)
Commitments and Contingencies [Line Items]                  
Purchase commitment amount under Insulin Supply Agreement | €           € 93.0      
Supply Agreement expiration period         Dec. 31, 2023 Dec. 31, 2023      
Supply Agreement renewal period         2 years 2 years      
Fair value of shares sold with warrants       $ 44,700,000 $ 11,000,000        
Exercise price of warrants | $ / shares       $ 7.50          
Number of warrant holders | shares   4              
Reclassification of warrant liability to additional paid-in capital   $ 1,900,000     1,893,000        
Common Stock | Subsequent Event                  
Commitments and Contingencies [Line Items]                  
Number of shares sold in underwritten public offering | shares 973,236                
Shares issuable under warrants granted | shares               1,292,510  
A Warrants                  
Commitments and Contingencies [Line Items]                  
Warrants expiration date       2018-05          
B Warrants                  
Commitments and Contingencies [Line Items]                  
Warrants expiration date       2018-11          
Warrants exercisable date       2017-05          
Registered Offering                  
Commitments and Contingencies [Line Items]                  
Number of shares sold in underwritten public offering | shares       9,708,737          
Maximum | A Warrants                  
Commitments and Contingencies [Line Items]                  
Warrants to purchase of common stock | shares       7,281,553          
Maximum | B Warrants                  
Commitments and Contingencies [Line Items]                  
Warrants to purchase of common stock | shares       2,427,184          
Scenario Forecast                  
Commitments and Contingencies [Line Items]                  
Purchase commitment cancellation fees             $ 3,400,000    
Scenario Forecast | Before Amendment                  
Commitments and Contingencies [Line Items]                  
Purchase commitment cancellation fees             $ 5,300,000    
Supply Commitment                  
Commitments and Contingencies [Line Items]                  
Purchase commitment obligation         500,000        
Deerfield | Milestone Rights Liability | Maximum                  
Commitments and Contingencies [Line Items]                  
Contingent liability for milestone payments         $ 90,000,000       $ 90,000,000
Russell Ranch Road II LLC [Member]                  
Commitments and Contingencies [Line Items]                  
Lease monthly rental payments     $ 40,951            
Percentage of annual increase in lease payment     3.00%            
Lease expiration date     Dec. 31, 2022            
Lease renewal option     5 years