Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016
Revenues:
Net revenue - commercial product sales	$ 1,981	$ 573	$ 4,726	$ 573
Net revenue - collaboration	62	161,781	187	161,781
Revenue - other			2,302
Total revenues	2,043	162,354	7,215	162,354
Expenses:
Cost of goods sold	4,575	4,394	12,210	12,912
Product costs - collaboration		22,742		22,742
Research and development	4,361	3,917	10,611	13,357
Selling, general and administrative	17,725	13,135	51,681	31,595
Property and equipment impairment	92		203	695
Loss on foreign currency translation	3,684	1,012	12,077	3,035
Gain on purchase commitment	(215)	(1,075)	(215)	(1,075)
Total expenses	30,222	44,125	86,567	83,261
(Loss) income from operations	(28,179)	118,229	(79,352)	79,093
Other income (expense):
Change in fair value of warrant liability	(1,289)	13,185	5,488	7,879
Interest income	65	28	178	70
Interest expense on notes	(2,310)	(4,166)	(7,438)	(12,567)
Interest expense on note payable to principal stockholder	(1,173)	(729)	(2,608)	(2,172)
Loss on extinguishment of debt			(830)
Other (expense) income		(27)	13	(613)
Total other (expense) income	(4,707)	8,291	(5,197)	(7,403)
(Loss) income before benefit for income taxes	(32,886)	126,520	(84,549)	71,690
Income tax benefit	0	0	0	0
Net (loss) income	$ (32,886)	$ 126,520	$ (84,549)	$ 71,690
Net (loss) income per share - basic	$ (0.31)	$ 1.32	$ (0.84)	$ 0.79
Net (loss) income per share - diluted	$ (0.31)	$ 1.31	$ (0.84)	$ 0.79
Shares used to compute basic net (loss) income per share	104,703	95,627	100,136	90,838
Shares used to compute diluted net (loss) income per share	104,703	96,549	100,136	90,873