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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
CASH FLOWS FROM OPERATING ACTIVITIES:      
Net income (loss) $ 5,863 $ 27,588 $ (11,938)
Adjustments to reconcile net income (loss) to net cash provided by operating activities:      
Stock-based compensation 24,195 21,358 17,649
Interest on liability for sale of future royalties 14,449 16,172 185
Sold portion of royalty revenue (12,811) (10,234) (2,103)
Write-off of inventory 10,397 3,855 4,574
Depreciation and amortization 12,284 7,371 4,535
Loss (gain) on foreign currency transaction 7,749 (3,907) 1,916
Impairment loss on available-for-sale investment 6,409 1,550 170
Net accretion of investments (2,647) (5,092) (925)
Non-cash lease expense of right-of-use assets 1,212 1,668 1,301
Change in fair value of contingent liability 1,029    
Amortization of debt discount and issuance costs 854 1,646 2,085
Loss on settlement of debt   20,444  
Gain on bargain purchase   (5,259)  
Loss on estimated returns of acquired product   1,444  
Other, net 155 380 (84)
Change in deferred tax liability (4,969)    
Changes in operating assets and liabilities:      
Accounts receivable, net (4,762) 2,652 2,345
Inventory (6,624) (3,196) (11,347)
Prepaid expenses and other current assets (10,032) (6,574) (7,318)
Other assets (1,909) (3,570) 263
Accounts payable (16,711) (2,788) (1,473)
Accrued expenses and other current liabilities 3,256 (2,703) 6,606
Deferred revenue (8,259) (15,312) 39,462
Recognized loss on purchase commitments   (2,690) (9,424)
Operating lease liabilities (873) (2,292) (2,385)
Net cash provided by operating activities 18,255 42,511 34,094
CASH FLOWS FROM INVESTING ACTIVITIES:      
Purchase of available-for-sale securities (157,803) (7,006)  
Proceeds from maturities of available-for-sale securities 215,308 58,126  
Acquisition of scPharma, net of cash acquired (347,742)    
Issuance of note receivable (10,000)    
Purchase of property and equipment (4,566) (9,693) (42,441)
Purchase of held-to-maturity securities   (273,789) (79,095)
Proceeds from maturities of held-to-maturity securities   135,317 119,166
Proceeds from insurance claim   396 382
Net cash used in investing activities (304,803) (96,649) (1,988)
CASH FLOWS FROM FINANCING ACTIVITIES:      
Proceeds from term loan 325,000    
Payment of loan issuance costs (7,266)    
Payments for taxes related to net issuance of common stock associated with restricted stock units and stock options (3,262) (6,087) (10,162)
Principal payments on financing liability (726) (398) (189)
Proceeds from market price stock purchase plan and employee stock purchase plan 1,992 3,139 1,820
Milestone Right Agreement payment (639) (752) (924)
Principal and early extinguishment payments on MidCap credit facility   (36,617) (6,667)
Proceeds from sale of future royalties     150,000
Issuance costs associated with sale of future royalties     (4,050)
Principal and early extinguishment payments on senior convertible notes   (87,697)  
Principal and early extinguishment payments on Mann Group convertible note   (8,854)  
Net cash provided by (used in) financing activities 315,099 (137,266) 136,607
NET INCREASE (DECREASE) IN CASH, CASH EQUIVALENTS AND RESTRICTED CASH 28,551 (191,404) 168,713
CASH, CASH EQUIVALENTS AND RESTRICTED CASH, BEGINNING OF PERIOD 47,076 238,480 69,767
CASH, CASH EQUIVALENTS AND RESTRICTED CASH, END OF PERIOD 75,627 47,076 238,480
SUPPLEMENTAL CASH FLOWS DISCLOSURES:      
Interest paid in cash 14,716 17,506 18,279
Income taxes paid in cash 1,705 4,262  
NON-CASH INVESTING AND FINANCING ACTIVITIES:      
Non-cash contingent consideration from acquisition of scPharma 25,217    
Debt forgiven as part of scPharma acquisition 10,000    
Payments of senior convertible note principal through common stock issuances   116,439  
Amortization of liability for sale of future royalties 1,407 3,605  
Purchases of property and equipment included in accounts payable and accrued expenses $ 619 1,679 1,691
Assumption of right-of-use-asset and operating lease liability   10,057  
Non-cash acquisition of intangible asset   4,300  
Non-cash acquisition of property and equipment   959  
Right-of-use asset modification     728
Goodwill adjustment for a net reduction in liabilities     497
Receivable for insurance claim on damaged equipment     445
Accrued issuance costs associated with liability for sale of future royalties     325
The Mann Group L L C      
NON-CASH INVESTING AND FINANCING ACTIVITIES:      
Payments of Mann Group principal and interest through common stock issuances   $ 3,806 222
At The Market Issuance      
CASH FLOWS FROM FINANCING ACTIVITIES:      
Proceeds from at-the-market-offering     6,887
Issuance costs associated with at-the-market offering     $ (108)