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Restructuring Charges - Additional Information (Detail)
$ in Millions
12 Months Ended
Dec. 31, 2015
USD ($)
Sep. 30, 2015
Employee
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Dec. 31, 2013
USD ($)
Restructuring Cost and Reserve [Line Items]          
Percentage of workforce reduction   26.00%      
Number of employees eliminated | Employee   198      
Restructuring charges     $ 5.9 $ 1.9 $ 0.4
Payment to restructuring $ 2.8        
Restucturing accrual $ 3.0   3.0 $ 0.3 $ 0.0
Research and development          
Restructuring Cost and Reserve [Line Items]          
Restructuring charges     3.0    
General and administrative          
Restructuring Cost and Reserve [Line Items]          
Restructuring charges     $ 2.9