Condensed Consolidated Statements of Cash Flows (Unaudited) (USD $) In Thousands, unless otherwise specified	9 Months Ended		260 Months Ended
	Sep. 30, 2012	Sep. 30, 2011	Sep. 30, 2012
CASH FLOWS FROM OPERATING ACTIVITIES:
Net Loss	$ (117,585)	$ (124,407)	$ (2,053,131)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation, amortization and accretion	10,929	12,097	123,304
Stock-based compensation expense	9,770	8,023	134,396
Stock expense for shares issued pursuant to research agreement			3,018
(Gain) loss on sale, abandonment/disposal or impairment of property and equipment	(73)	(63)	23,498
Accrued interest on investments, net of amortization of discounts			(191)
In-process research and development			19,726
Goodwill impairment			151,428
Loss on available-for-sale securities	117		990
Fair value of forward purchase contract	(12,011)		(12,011)
Other, net	(4)		1,097
Changes in assets and liabilities:
State research and development credit exchange receivable	(270)	152	(743)
Prepaid expenses and other current assets	(18,007)	(111)	(19,032)
Other assets		87	(230)
Accounts payable	(1,526)	(121)	2,848
Accrued expenses and other current liabilities	36,898	861	56,872
Other liabilities			(2)
Net cash used in operating activities	(91,762)	(103,482)	(1,568,163)
CASH FLOWS FROM INVESTING ACTIVITIES:
Purchase of marketable securities			(796,779)
Sales and maturities of marketable securities		3,828	796,393
Purchase of property and equipment	(572)	(6,703)	(327,681)
Proceeds from sale of property and equipment	73	63	450
Net cash used in investing activities	(499)	(2,812)	(327,617)
CASH FLOWS FROM FINANCING ACTIVITIES:
Issuance of common stock and warrants, net of issuance costs	80,982	10,544	1,311,003
Collection of Series C convertible preferred stock subscriptions receivable			50,000
Issuance of Series B convertible preferred stock for cash			15,000
Cash received for common stock to be issued			3,900
Repurchase of common stock			(1,028)
Put shares sold to majority stockholder			623
Borrowings under lines of credit			4,220
Proceeds from notes receivables			1,742
Borrowings on notes payable to related party	11,250	53,000	386,250
Principal payments on notes payable to principal stockholder			(70,000)
Borrowings on notes payable			3,460
Principal payments on notes payable			(1,667)
Proceeds from senior convertible notes			207,050
Payment of employment taxes related to vested restricted stock units	(887)	(525)	(13,008)
Net cash provided by financing activities	91,345	63,019	1,897,545
NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS	(916)	(43,275)	1,765
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD	2,681	66,061
CASH AND CASH EQUIVALENTS, END OF PERIOD	1,765	22,786	1,765
SUPPLEMENTAL CASH FLOWS DISCLOSURES:
Cash paid for income taxes			26
Interest paid in cash, net of amounts capitalized	7,626	15,092	57,023
Accretion on redeemable convertible preferred stock			(952)
Issuance of common stock upon conversion of notes payable			3,331
Increase in additional paid-in capital resulting from merger			171,154
Issuance of common stock for notes receivable			2,758
Issuance of put option by stockholder			(2,949)
Put option redemption by stockholder			1,921
Issuance of Series C convertible preferred stock subscriptions			50,000
Issuance of Series A redeemable convertible preferred stock			4,296
Conversion of Series A redeemable convertible preferred stock			(5,248)
Non-cash construction in progress and property and equipment	2,907	181	2,907
Capitalization of interest on note payable to related party	11,876		11,876
Reduction of principal on note payable to related party upon issuance of common stock	77,187	11,116	104,984
Forward purchase contract contribution to additional paid-in capital	1,080		1,080
Reclassification of forward purchase contract to additional paid-in capital	$ 13,091		$ 13,091